Evidence map›Paper›PMID 41172514›Full record

ArticleArquivos brasileiros de oftalmologia2025

Diagnostic accuracy of a deep learning model for pterygium detection in Barcelos, Brazilian Amazon.

Diego Casagrande, Mauro Gobira, Arthur G Fernandes, Marcos Jacob Cohen, Paula Marques Marinho, Kevin Waquim Pessoa Carvalho, Ariane Luttecke-Anders, Beatriz Araujo Stauber, Nívea Nunes Ferraz, Jacob Moysés Cohen and 3 more

Abstract read
In one paragraph

Article in Arquivos brasileiros de oftalmologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Diego CasagrandeInstituto da Visão, Instituto Paulista de Estudos e Pesquisas em Oftalmologia, São Paulo, SP, Brazil.ORCID 0000-0001-5158-5457
Mauro GobiraInstituto da Visão, Instituto Paulista de Estudos e Pesquisas em Oftalmologia, São Paulo, SP, Brazil.ORCID 0000-0002-0483-8789
Arthur G FernandesDepartment of Ophthalmology and Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0002-7525-1838
Marcos Jacob CohenDivision of Ophthalmology, Department of Surgery, Faculdade de Medicina, Universidade Federal do Amazonas, Manaus, AM, Brazil.ORCID 0000-0002-0480-4036
Paula Marques MarinhoInstituto da Visão, Instituto Paulista de Estudos e Pesquisas em Oftalmologia, São Paulo, SP, Brazil.ORCID 0000-0001-7904-4169
Kevin Waquim Pessoa CarvalhoInstituto da Visão, Instituto Paulista de Estudos e Pesquisas em Oftalmologia, São Paulo, SP, Brazil.ORCID 0000-0002-3923-0503
Ariane Luttecke-AndersDepartment of Ophthalmology and Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0001-8047-4625
Beatriz Araujo StauberDepartment of Ophthalmology and Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.ORCID 0009-0005-8605-4337
Nívea Nunes FerrazDepartment of Ophthalmology and Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0001-7568-6199
Jacob Moysés CohenDivision of Ophthalmology, Department of Surgery, Faculdade de Medicina, Universidade Federal do Amazonas, Manaus, AM, Brazil.ORCID 0000-0002-9071-6234
Adriana BerezovskyDepartment of Ophthalmology and Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0001-6350-8221
Solange Rios SalomãoDepartment of Ophthalmology and Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0002-3436-5599
Rubens BelfortInstituto da Visão, Instituto Paulista de Estudos e Pesquisas em Oftalmologia, São Paulo, SP, Brazil.ORCID 0000-0002-8422-3898

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis pilot study evaluated the diagnostic accuracy of a deep learning model for detecting pterygium in anterior segment photographs taken using smartphones in the Brazilian Amazon. The model's performance was benchmarked against assessments made by experienced ophthalmologists, considered the clinical gold standard.

methodsIn this cross-sectional study, 38 participants (76 eyes) from Barcelos, Brazil, were enrolled. Trained nonmedical health workers captured high-resolution anterior segment images using smartphones. These images were analyzed using a deep learning model based on the MobileNet-V2 convolutional neural network. Diagnostic metrics-including sensitivity, specificity, accuracy, positive predictive value, negative predictive value, and area under the receiver operating characteristic curve-were calculated and compared with the ophthalmologists' evaluations.

resultsThe deep learning model achieved a sensitivity of 91.43%, specificity of 90.24%, positive predictive value of 88.46%, negative predictive value of 92.79%, and an area under the curve of 0.91. Logistic regression revealed no statistically significant association between pterygium and demographic variables such as age or gender.

conclusionsThe deep learning model demonstrated high diagnostic performance in identifying pterygium in a remote Amazonian population. These preliminary findings support the potential use of artificial intelligence-based tools to facilitate early detection and screening in underserved regions, thereby enhancing access to ophthalmic care.

Indexed as

Deep LearningPterygiumAdultAgedBrazilCross-Sectional StudiesFemaleHumansMaleMiddle AgedPhotographyPilot ProjectsPredictive Value of TestsReproducibility of ResultsROC CurveSensitivity and Specificity

Identifiers

PMID41172514
PMCPMC12997579

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.