Evidence map›Paper›PMID 41172512›Full record

ArticleMemorias do Instituto Oswaldo Cruz2025

First isolation of Mycobacterium brisbanense from humans in the Americas.

Carlos Eduardo Dias Campos, Rachel Dos Santos de Sena Vasconcelos, William Marco Vicente da Silva, Luciana Distásio de Carvalho, Melissa de Almeida Barbosa Eccard, Isabelle Pinheiro Nobre Dos Santos, Jesus Pais Ramos

Abstract read
In one paragraph

Article in Memorias do Instituto Oswaldo Cruz, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carlos Eduardo Dias CamposFundação Oswaldo Cruz-Fiocruz, Escola Nacional de Saúde Pública, Centro de Referência Professor Hélio Fraga, Laboratório de Referência Nacional de Tuberculose e Micobacterioses, Rio de Janeiro, RJ, Brasil.
Rachel Dos Santos de Sena VasconcelosFundação Oswaldo Cruz-Fiocruz, Escola Nacional de Saúde Pública, Centro de Referência Professor Hélio Fraga, Laboratório de Referência Nacional de Tuberculose e Micobacterioses, Rio de Janeiro, RJ, Brasil.
William Marco Vicente da SilvaFundação Oswaldo Cruz-Fiocruz, Escola Nacional de Saúde Pública, Centro de Referência Professor Hélio Fraga, Laboratório de Referência Nacional de Tuberculose e Micobacterioses, Rio de Janeiro, RJ, Brasil.
Luciana Distásio de CarvalhoFundação Oswaldo Cruz-Fiocruz, Escola Nacional de Saúde Pública, Centro de Referência Professor Hélio Fraga, Laboratório de Referência Nacional de Tuberculose e Micobacterioses, Rio de Janeiro, RJ, Brasil.
Melissa de Almeida Barbosa EccardFundação Oswaldo Cruz-Fiocruz, Escola Nacional de Saúde Pública, Centro de Referência Professor Hélio Fraga, Laboratório de Referência Nacional de Tuberculose e Micobacterioses, Rio de Janeiro, RJ, Brasil.
Isabelle Pinheiro Nobre Dos SantosFundação Oswaldo Cruz-Fiocruz, Escola Nacional de Saúde Pública, Centro de Referência Professor Hélio Fraga, Laboratório de Referência Nacional de Tuberculose e Micobacterioses, Rio de Janeiro, RJ, Brasil.
Jesus Pais RamosFundação Oswaldo Cruz-Fiocruz, Escola Nacional de Saúde Pública, Centro de Referência Professor Hélio Fraga, Laboratório de Referência Nacional de Tuberculose e Micobacterioses, Rio de Janeiro, RJ, Brasil.ORCID http://orcid.org/0000-0002-4183-5915

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMycobacterium brisbanense is a rare nontuberculous mycobacteria and was for the first time detected in the Americas in humans. However, this, like several other species of mycobacteria, may be underreported worldwide. Therefore, their study is increasingly important.

objectivesThe aim of this article is to report and analyse the first seven human isolates of M. brisbanense in the Americas, derived from six Brazilian patients.

methodsWe sequenced the genes hsp65, rpoB and 16s rRNA, of seven mycobacterial clinical isolates, constructed a phylogenetic tree, and determined their drug susceptibility profile.

findingsThe regions sequenced were highly similar between the M. brisbanense type strain and the Brazilian strains. Similarly, their susceptibility profiles were similar to that of M. brisbanense type strain, except for two antibiotics tested, cefoxitin and doxycycline. MAIN

conclusionsAll studied strains were identified at the species level by a concatenated tree as M. brisbanense.

Indexed as

MycobacteriumMycobacterium Infections, NontuberculousNontuberculous MycobacteriaAdultAnti-Bacterial AgentsBacterial ProteinsBrazilChaperonin 60DNA, BacterialFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedPhylogenyPolymerase Chain ReactionAnti-Bacterial AgentsBacterial ProteinsChaperonin 60DNA, Bacterialheat-shock protein 65, MycobacteriumRNA, Ribosomal, 16S

Identifiers

PMID41172512
PMCPMC12551999

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.