Evidence map›Paper›PMID 41172300›Full record

ArticleJMIR research protocols2025

Implementation, Experiences, Impact, and Costs of Artificial Intelligence in Chest Diagnostics: Protocol for a Mixed Methods Evaluation.

Angus I G Ramsay, Chris Sherlaw-Johnson, Kevin Herbert, Stuti Bagri, Malina Bodea, Nadia Crellin, Holly Elphinstone, Amanda Halliday, Nina Hemmings, Rachel Lawrence and 9 more

Abstract read
In one paragraph

Article in JMIR research protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Angus I G RamsayDepartment of Behavioural Science and Health, Institute of Epidemiology and Healthcare, University College London, London, United Kingdom.ORCID 0000-0002-4446-6916
Chris Sherlaw-JohnsonNuffield Trust, London, United Kingdom.ORCID 0000-0002-4851-6060
Kevin HerbertDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.ORCID 0009-0008-4354-7811
Stuti BagriNuffield Trust, London, United Kingdom.ORCID 0009-0005-1267-2503
Malina BodeaNuffield Trust, London, United Kingdom.ORCID 0009-0004-5272-6257
Nadia CrellinNuffield Trust, London, United Kingdom.ORCID 0000-0002-9497-5874
Holly ElphinstoneDepartment of Behavioural Science and Health, Institute of Epidemiology and Healthcare, University College London, London, United Kingdom.ORCID 0009-0007-3850-2128
Amanda HallidayPublic Contributor, Cambridgeshire, United Kingdom.ORCID 0009-0002-5905-0566
Nina HemmingsNuffield Trust, London, United Kingdom.ORCID 0009-0002-1911-3630
Rachel LawrenceDepartment of Behavioural Science and Health, Institute of Epidemiology and Healthcare, University College London, London, United Kingdom.ORCID 0000-0003-3743-4622
Cyril LobontNuffield Trust, London, United Kingdom.ORCID 0009-0006-0031-2129
Pei Li NgDepartment of Behavioural Science and Health, Institute of Epidemiology and Healthcare, University College London, London, United Kingdom.ORCID 0000-0001-8411-220X
Joanne LloydPublic Contributor, Devon, United Kingdom.ORCID 0009-0007-7419-1662
Efthalia MassouDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0003-0488-482X
Raj MehtaPublic Contributor, London, United Kingdom.ORCID 0000-0002-4003-530X
Stephen MorrisDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-5828-3563
Jenny ShandDepartment of Behavioural Science and Health, Institute of Epidemiology and Healthcare, University College London, London, United Kingdom.ORCID 0000-0002-4899-795X
Holly WaltonDepartment of Behavioural Science and Health, Institute of Epidemiology and Healthcare, University College London, London, United Kingdom.ORCID 0000-0002-8746-059X
Naomi J FulopDepartment of Behavioural Science and Health, Institute of Epidemiology and Healthcare, University College London, London, United Kingdom.ORCID 0000-0001-5306-6140

Funding

National Institute for Health and Care Research, Health and Social Care Delivery Research NIHR156380
6 · The paper itself

Abstract

backgroundThe ability to perform complex tasks has seen artificial intelligence (AI) used to support radiology in clinical settings, including lung cancer detection and diagnosis. Evidence suggests that AI can contribute to accurate diagnosis, reduce errors, and improve efficiency. The National Health Service England (NHSE)-funded Artificial Intelligence Diagnostic Fund (AIDF) is currently supporting 12 National Health Service (NHS) networks to implement AI for chest diagnostic imaging. There is, however, limited evidence on real-world AI implementation and use, including staff, patient, and caregiver experience, and costs and cost-effectiveness. A National Institute for Health and Care Research Rapid Service Evaluation Team Phase 1 evaluation provided insights into the early implementation of these tools and developed a framework for monitoring and evaluation of AI tools for chest diagnostic imaging in practice.

objectiveThis mixed methods evaluation of AI tools for chest diagnostic imaging aims to address previous research gaps by exploring the implementation of AI tools for chest diagnostic imaging, the impact and costs of implementing these service models, and the experiences of patients, caregivers, and staff.

methodsThis study will be a mixed method evaluation of implementation, experiences, impact, and costs of AI for chest diagnostic imaging in NHS services in England, with the evaluation informed by the Major System Change Framework. Trust-level case studies (3 in-depth and up to 9 light-touch) will be performed, including staff member, patient, and caregiver; NHSE AIDF team interviews; meeting observations; and analysis of key relevant documentation. Qualitative data will be analyzed using Rapid Assessment Procedures and inductive thematic analysis, supplemented by in-depth deductive thematic analysis. Data from case study sites and other relevant sources will be used to assess outcomes at the other sites and for comparators. A pragmatic economic model of the chest diagnostic imaging pathway will be developed to estimate key costs and resource use associated with AI tool deployment. Together with input from national stakeholders and staff workshops, the study findings will then be finalized for reporting.

resultsAs of September 2025, trust-level research and development approvals with participating sites are complete, and data collection has commenced. Results are expected to be reported by the end of February 2026.

conclusionsThe study will provide new insights into the facilitators and barriers to the adoption of AI technology in health care and the perceptions of both the general public and health care staff on its use. It will also inform best practices in approaches for service performance evaluation, for the implementation of AI into existing care pathways, and for the development of models to best support evidence-based decision-making. It will thus establish a framework upon which the greatest benefits of the use of AI in health care can be realized. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/81421.

Indexed as

Artificial IntelligenceLung NeoplasmsThoraxCost-Benefit AnalysisEnglandHumansResearch DesignState Medicineartificial intelligencecost-effectivenessdiagnostic imaginglung cancermixed methods evaluationpatient experiencepatient outcomes

Identifiers

PMID41172300
PMCPMC12619010

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.