Evidence map›Paper›PMID 41172046›Full record

ArticleScience progress

Identification of red cell distribution width trajectory patterns and their association with 28-day mortality in intensive care unit patients with atrial fibrillation: A latent class analysis.

Xin Zuo, Huan Zuo, Min Zhang

Abstract read
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Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Xin ZuoDepartment of Acupuncture and Moxibustion, Heilongjiang University of Traditional Chinese Medicine, Harbin, China.
Huan ZuoDepartment of Acupuncture and Moxibustion, Heilongjiang University of Traditional Chinese Medicine, Harbin, China.ORCID 0009-0004-9522-5129
Min ZhangDepartment of Neurology, Xiamen Humanity Hospital, Fujian Medical University, Xiamen, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundRed cell distribution width (RDW) has been identified as a potential prognostic marker in multiple cardiovascular and critical illnesses. Nevertheless, its prognostic value, particularly regarding changes in RDW over time among patients with atrial fibrillation (AF), remains uncertain.MethodsA retrospective cohort study was conducted using data from the Medical Information Mart for Intensive Care (MIMIC)-IV database. The study included adult intensive care unit (ICU) patients with AF who had at least three RDW measurements within the first 36 h of ICU admission. Latent growth mixture modeling (LGMM) was applied to identify distinct RDW progression patterns over time. The association between the identified RDW trajectory groups and 28-day mortality was assessed using Cox proportional hazard regression. Kaplan-Meier survival curves and subgroup analyses were also conducted.ResultsA total of 3509 patients were enrolled in the analysis. LGMM identified three distinct RDW trajectories: Class 1 (stable and low RDW), Class 2 (moderate with a rising RDW) and Class 3 (high with fluctuating RDW). After adjusting for demographics, clinical parameters, comorbidities and treatments, Class 2 remained independently associated with higher 28-day mortality compared with Class 1 (

Indexed as

Atrial FibrillationErythrocyte IndicesAgedCritical IllnessFemaleHospital MortalityHumansIntensive Care UnitsKaplan-Meier EstimateLatent Class AnalysisMaleMiddle AgedPrognosisRetrospective StudiesAtrial fibrillationlatent class modelingMIMIC-IVred cell distribution widthtrajectory analysis

Identifiers

PMID41172046
PMCPMC12579733

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.