Evidence map›Paper›PMID 41171923›Full record

ArticleScience advances2025

Tardigrade Dsup extends

Myriam Richaud, Rohit Shrivastava, Dimitris Xirodimas, Simon Galas, Aymeric Bailly

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Myriam RichaudIBMM, University of Montpellier, CNRS, ENSCM, Montpellier, France.ORCID 0000-0002-7720-8569
Rohit ShrivastavaCRBM, University of Montpellier, CNRS UMR5237, BIOLuM, Montpellier, France.ORCID 0000-0001-7983-6510
Dimitris XirodimasCRBM, University of Montpellier, CNRS UMR5237, BIOLuM, Montpellier, France.ORCID 0000-0001-9275-1140
Simon GalasIBMM, University of Montpellier, CNRS, ENSCM, Montpellier, France.ORCID 0000-0002-1717-1266
Aymeric BaillyCRBM, University of Montpellier, CNRS UMR5237, BIOLuM, Montpellier, France.ORCID 0000-0002-0842-5631

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tardigrades survive extreme environments partly through the damage suppressor (Dsup) protein, which protects DNA from ionizing radiation and oxidative stress. Dsup is largely unstructured but binds nucleosomes to shield DNA from damage. To investigate its protective role in a whole organism, we expressed the

Indexed as

Caenorhabditis elegansLongevityMitochondriaOxidative StressTardigradaAnimalsAnimals, Genetically ModifiedCaenorhabditis elegans ProteinsCell RespirationCaenorhabditis elegans Proteins

Identifiers

PMID41171923
PMCPMC12577708

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.