Evidence map›Paper›PMID 41171916›Full record

ArticleScience advances2025

Salicylic acid and ROS signaling modulate hypocotyl elongation in darkness via NPR1 and EX1.

Mengshuang Li, Mengping Li, Shan Qi, Liangsheng Wang, Chanhong Kim

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Singlet Oxygen Generation and Signaling in Higher Plants.International journal of molecular sciences · 2026
    Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mengshuang LiShanghai Center for Plant Stress Biology, Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 200032, China.ORCID 0009-0000-5213-8392
Mengping LiShanghai Center for Plant Stress Biology, Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 200032, China.ORCID 0000-0002-3659-6251
Shan QiShanghai Center for Plant Stress Biology, Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 200032, China.ORCID 0000-0003-2851-6300
Liangsheng WangState Key Laboratory of Plant Environmental Resilience, College of Biological Sciences, China Agricultural University, Beijing 100193, China.
Chanhong KimShanghai Center for Plant Stress Biology, Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 200032, China.ORCID 0000-0003-4133-9070

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During early seedling growth in darkness, germinating seeds must balance growth and defense to ensure a successful transition from a heterotrophic to a photoautotrophic state. However, the molecular mechanisms regulating this process in etiolated seedlings remain poorly understood. Here, we investigate the role of salicylic acid (SA), a key defense hormone, in controlling hypocotyl elongation under dark conditions. SA inhibited hypocotyl growth in a dose-dependent manner, with a more substantial effect in the

Indexed as

ArabidopsisArabidopsis ProteinsDarknessHypocotylReactive Oxygen SpeciesSalicylic AcidSignal TransductionGene Expression Regulation, PlantIndoleacetic AcidsSeedlingsArabidopsis ProteinsIndoleacetic AcidsNPR1 protein, ArabidopsisReactive Oxygen SpeciesSalicylic Acid

Identifiers

PMID41171916
PMCPMC12577707

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.