ArticleAnalytical chemistry2025
SMART 2.0 Statistical Metabolomics Analysis: An R Tool 2.0.
Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolomics has experienced significant growth and increased popularity due to technological advancements. We introduced an integrated tool for untargeted metabolomics analysis, SMART 1.0, that streamlined the entire analysis process, from initial data preprocessing to subsequent association analysis. With SMART 2.0, we enhanced SMART 1.0 by introducing new analytical modules in targeted metabolomics analysis, data normalization, quality control assessment, and advanced dimensionality reduction and classification methods. Additionally, SMART 2.0 offers integrative omics pathway analysis and postanalysis tasks such as peak identification and concentration calibration. We also explored the potential of using large language models for peak annotation and have found the results to be promising. This study employs narcotics data and breast cancer data as demonstrative examples to illustrate the new functionalities. The codes, a user guide, and example data can be downloaded at https://github.com/YuJenL/SMART.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.