Evidence map›Paper›PMID 41171752›Full record

ArticleEuropean heart journal open2025

Development of three-step holistic care pathways to detect and manage comorbidities in patients with atrial fibrillation: the Horizon 2020 EHRA-PATHS consortium.

Rana Önder, Lien Desteghe, Johan Vijgen, Rónán Collins, Rafal Dabrowski, Michal Miroslaw Farkowski, Marcio Jansen de Oliveira Figueiredo, Maartje J M Hereijgers, Daniel Hofer, Chu-Pak Lau and 15 more

Abstract readComment
In one paragraph

Article in European heart journal open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Assessment of comorbidity awareness in patients with atrial fibrillation: The ACAPAF study.International journal of cardiology. Heart & vasculature · 2025
    Article
  2. Implementation of new concise care pathways into a software tool to detect and manage comorbidities in older patients with atrial fibrillation: the Horizon 2020 EHRA-PATHS project.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors.

Rana ÖnderFaculty of Medicine and Life Sciences, Hasselt University, Martelarenlaan 42, Hasselt 3500, Belgium.ORCID https://orcid.org/0000-0002-9305-634X
Lien DestegheFaculty of Medicine and Life Sciences, Hasselt University, Martelarenlaan 42, Hasselt 3500, Belgium.ORCID https://orcid.org/0000-0001-8641-4658
Johan VijgenFaculty of Medicine and Life Sciences, Hasselt University, Martelarenlaan 42, Hasselt 3500, Belgium.ORCID https://orcid.org/0000-0003-4928-4836
Rónán CollinsDepartment of Gerontology Trinity College and Tallaght University Hospital, Tallaght, Dublin D24 NR0A, Ireland.ORCID https://orcid.org/0000-0003-0404-8266
Rafal DabrowskiDepartment of Coronary Artery Disease and Cardiac Rehabilitation, National Institute of Cardiology, Alpejska 42, Warsaw 04-628, Poland.ORCID https://orcid.org/0000-0002-5602-0313
Michal Miroslaw FarkowskiDepartment of Cardiology, Ministry of Interior and Administration National Medical Institute, Woloska 137, Warsaw 02-507, Poland.ORCID https://orcid.org/0000-0003-1673-7712
Marcio Jansen de Oliveira FigueiredoDepartment of Cardiology, University of Campinas (UNICAMP) Medical School, Campinas, R. Tessalia Vieira de Camargo 126, Sao Paulo 13083-887, Brazil.ORCID https://orcid.org/0000-0002-3477-4667
Maartje J M HereijgersDepartment of Cardiology and Respiratory Medicine, Maastricht University Medical Centre +, P. Debyelaan 25, Maastricht 6229 HX, the Netherlands.ORCID https://orcid.org/0000-0002-8896-6293
Daniel HoferDepartment of Cardiology, University Hospital Zurich, Rämistrasse 100, Zurich 8091, Switzerland.ORCID https://orcid.org/0000-0001-8164-6329
Chu-Pak LauThe Department of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR, China.ORCID https://orcid.org/0000-0002-3526-8950
Geraldine LeeSchool of Nursing & Midwifery, Brookfield Health Sciences Complex, University College Cork, Cork T12 AK54, Ireland.ORCID https://orcid.org/0000-0001-6385-8600
Dominik LinzDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Universiteitssingel 50, Maastricht 6629 ER, The Netherlands.ORCID https://orcid.org/0000-0003-4893-0824
Michelle LobeekDepartment of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0009-0003-0531-6741
Teresa LopezDepartment of Cardiology, Cardio-Oncology Unit, La Paz University Hospital, IdiPAZ Research Institute, Paseo de la Castellena 261, Madrid 28046, Spain.ORCID https://orcid.org/0000-0002-3414-7022
Christine McAuliffePharmacy Department, Tallaght University Hospital, Tallaght, Dublin D24 NR0A, Ireland.ORCID https://orcid.org/0009-0009-9398-4339
Jose Luis MerinoDepartment of Cardiology, La Paz University Hospital, Paseo de la Castellena 261, Madrid 28046, Spain.ORCID https://orcid.org/0000-0002-1737-1903
Tatjana PotparaFaculty of Medicine, Belgrade University, Dr. Subotica-starijeg 8, Belgrade 11000, Serbia.ORCID https://orcid.org/0000-0001-6285-6902
Prashanthan SandersCentre for Heart Rhythm Disorders, University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia.ORCID https://orcid.org/0000-0003-3803-8429
Alireza Sepehri ShamlooDepartment of Cardiology, Deutsches Herzzentrum der Charité-Medical Heart Center of Charité, German Heart Institute Berlin, Augustenburger Platz 1, Berlin 13353, Germany.ORCID https://orcid.org/0000-0002-4894-8664
Maciej Sterliński1st Arrhythmia Department, National Institute of Cardiology, Alpejska 42, Warszawa 04-628, Poland.
Emma SvennbergKarolinska Institutet, Department of Medicine (MedH), Karolinska University Hospital Huddinge, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-6413-0870
Colinda van DeutekomDepartment of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0001-5116-7378
Isabelle Van GelderDepartment of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0002-7579-1201
Michiel RienstraDepartment of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0002-2581-070X
Hein HeidbuchelFaculty of Medicine and Life Sciences, Hasselt University, Martelarenlaan 42, Hasselt 3500, Belgium.ORCID https://orcid.org/0000-0001-9301-8127

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Older patients with AF (≥65 years) have on average four additional comorbidities. Comorbidity management requires a systematic approach for identification, and interdisciplinary care, often lacking in clinical practice. The EHRA-PATHS project's overall aim is to create an approach to systematically address multimorbidity in older patients with AF. Methods and results: This project involves a consortium of 14 partners from 11 European countries. The comorbidity care pathways were developed using a stepwise approach. (i) A literature study. (ii) Online meetings/discussions to create structured care pathways. (iii) A two-round Delphi study for consensus on the final pathways (agreement ≥80%) and to rank the comorbidities for priority. (iv) Selection of comorbidities for evaluation in the planned randomized controlled trial (RCT). Development of care pathways for 23 comorbidities or special clinical settings was obtained and agreed upon. The Delphi surveys were sent to 37 consortium experts. After round 1 (28 responses), 13 pathways reached an agreement ≥80%. Twelve adjusted pathways were presented in round 2 (27 responses), of which 8 received an agreement ≥80%. The last four pathways were finalized after expert consensus. Hypertension, heart failure, and overweight were ranked as the most important comorbidities. Conclusion: A structured process of expert meetings and two Delphi rounds led to the development and ranking of 23 concise care pathways to identify and manage comorbidities in patients with AF. All pathways will be combined into a software tool, providing clinicians with a systematic approach to comorbidity management, which will be tested in the RCT of EHRA-PATHS.

Indexed as

Atrial fibrillationCare pathwaysMultimorbidity

Identifiers

PMID41171752
PMCPMC12555002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.