Evidence map›Paper›PMID 41171750›Full record

ArticlePloS one2025

Utilization of interdisciplinary in-hospital early rehabilitation in COVID-19 patients - a multicenter cohort study in the National Pandemic Cohort Network (NAPKON) in Germany.

Max E Liebl, Anett Reisshauer, Dana Loudovici-Krug, Philipp Baumbach, Katharina S Appel, Sabine Blaschke, Johanna Erber, Ilka Grewe, Marina Hagen, Ekaterina Heim and 13 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Max E LieblDepartment of Physical and Rehabilitation Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany.ORCID 0000-0002-6608-4281
Anett ReisshauerDepartment of Physical and Rehabilitation Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany.
Dana Loudovici-KrugUniversity Hospital Jena, Institute of Physical and Rehabilitation Medicine, Friedrich-Schiller University Jena, Jena, Germany.
Philipp BaumbachDepartment for Anesthesiology and Intensive Care Medicine, University Hospital Jena, Friedrich-Schiller University Jena, Jena, Germany.ORCID 0000-0002-7815-6924
Katharina S AppelFaculty of Medicine, Goethe University Frankfurt, Institute for Digital Medicine and Clinical Data Science, Frankfurt, Germany.
Sabine BlaschkeCentral Emergency Department, University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0001-8800-7554
Johanna ErberTUM School of Medicine and Health - Clinical Department for Internal Medicine II, TUM University Hospital, Technical University of Munich, Munich, Germany.
Ilka GreweI. Department of Medicine, University Medical Center Hamburg-Eppendorf, Institute for Infection Research and Vaccine Development, Hamburg, Germany.
Marina HagenDepartment II of Internal Medicine, Hematology/Oncology, Goethe University, Frankfurt, Germany.
Ekaterina HeimTrusted Third Party of the University Medicine Greifswald, Greifswald, Germany.
Sina M PützFaculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, University of Cologne, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Cologne, Germany.
Kristin LehnertDZHK (German Center for Cardiovascular Research), University Medicine Greifswald, Greifswald, Germany.
Patrick MeybohmDepartment of Anaesthesiology, University Hospital Würzburg, Intensive Care, Emergency and Pain Medicine, Würzburg, Germany.
Olga MiljukovUniversity of Würzburg, Institute for Clinical Epidemiology and Biometry, Würzburg, Germany.ORCID 0000-0003-4790-5918
Milena MilovanovicMalteser Krankenhaus St. Franziskus Hospital, Medical Clinic I, Flensburg, Germany.
Susana M Nunes de MirandaFaculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, University of Cologne, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Cologne, Germany.
Christoph RömmeleInternal Medicine III - Gastroenterology and Infectious Diseases, University Hospital of Augsburg, Augsburg, Germany.
Phil-Robin TepasseDepartment of Medicine B for Gastroenterology, University Hospital Münster, Hepatology, Endocrinology and Clinical Infectiology, Münster, Germany.
Jörg J VehreschildFaculty of Medicine, Goethe University Frankfurt, Institute for Digital Medicine and Clinical Data Science, Frankfurt, Germany.
Norman WeinertDepartment of Medical Informatics, University Medical Center Göttingen, Göttingen, Germany.
Martin WeiglDepartment of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Germany.
Julia WendelUniversity of Würzburg, Institute for Clinical Epidemiology and Biometry, Würzburg, Germany.
Christina LemhöferUniversity Hospital Jena, Institute of Physical and Rehabilitation Medicine, Friedrich-Schiller University Jena, Jena, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly rehabilitation in acute hospitals aims to prevent immobilization-related complications and improve the functional capacity of patients with severe or critical illness. Early rehabilitation can be a useful concept to improve functioning in COVID-19 patients. However, literature concerning early in-hospital rehabilitation in COVID-19 patients is scarce.

aimTo analyze the utilization of in-hospital interdisciplinary early rehabilitation (IER) in COVID-19 patients and characterize the sample of IER patients.

designProspective cohort study.

settingHospitalized COVID-19 patient cases. POPULATION: This study used data from the National Pandemic Cohort Network (NAPKON) in Germany.

methodsIER utilization rates were retrieved. Demographic and clinical data from hospitalized COVID-19 patients who had received IER during the course of their treatment were evaluated.

resultsOut of the 2,644 patients in the Cross-Sectoral Platform (German abbreviation: SUEP) cohort, 0.79% [95% CI: 0.51% to 1.22%] received IER during their stay in an acute care hospital. Among the subgroup of patients who had previously been treated in intensive care, 2.13% [95% CI: 1.16% to 3.63%] received IER. The most common comorbidities were cardiovascular diseases (66.7%) and neurological/psychiatric diseases (36.1%). The small sample size limited further analyses.

conclusionThe low rate of early rehabilitation in acute hospitals for COVID-19 patients indicates an unmet need, particularly in severe cases. Structural changes in the health system are needed to close this gap. The WHO and the German Medical Council have recently acknowledged the necessity of early in-hospital rehabilitation and have issued a call for its implementation in acute hospitals.

Indexed as

COVID-19AdultAgedAged, 80 and overCohort StudiesFemaleGermanyHospitalizationHumansMaleMiddle AgedPandemicsProspective StudiesSARS-CoV-2

Identifiers

PMID41171750
PMCPMC12578259

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.