Evidence map›Paper›PMID 41171621›Full record

ArticleCancer science2026

The LGALS9/miR-491-5p Axis Regulates CD8

Wanzhong Huang, Wei Zheng, Dagao Zhu, Zhi Sun, Wei Lu, Jun Tao, Chen Liu, Liangliang Li, Yingli Zhou, Honghong Fan and 2 more

Abstract read
In one paragraph

Article in Cancer science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wanzhong HuangDepartment of Medical Oncology, Tonglin People's Hospital, Tonglin, Anhui, China.ORCID https://orcid.org/0000-0003-3930-8523
Wei ZhengDepartment of Medical Oncology, Tonglin People's Hospital, Tonglin, Anhui, China.
Dagao ZhuDepartment of Medical Oncology, Tonglin People's Hospital, Tonglin, Anhui, China.
Zhi SunDepartment of Gastrointestinal Surgery, Tonglin People's Hospital, Tonglin, Anhui, China.
Wei LuDepartment of Gastrointestinal Surgery, Tonglin People's Hospital, Tonglin, Anhui, China.
Jun TaoDepartment of Gastrointestinal Surgery, Tonglin People's Hospital, Tonglin, Anhui, China.
Chen LiuDepartment of Pathology, Tonglin People's Hospital, Tonglin, Anhui, China.
Liangliang LiDepartment of Medical Oncology, Tonglin People's Hospital, Tonglin, Anhui, China.
Yingli ZhouDepartment of Medical Oncology, Tonglin People's Hospital, Tonglin, Anhui, China.
Honghong FanDepartment of Medical Oncology, Tonglin People's Hospital, Tonglin, Anhui, China.
Hong TaoDepartment of Medical Oncology, Tonglin People's Hospital, Tonglin, Anhui, China.
Wenjuan LiDepartment of Medical Oncology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.

Funding

Natural Science Projects of Bengbu Medical College 2023BYZD013
6 · The paper itself

Abstract

Gastric cancer is a prevalent and clinically significant gastrointestinal malignancy worldwide. Gastric cancer is characterized by limited treatment efficacy and a high recurrence rate. In this study, we found that LGALS9 was highly expressed in gastric cancer and may contribute to disease progression by modulating the infiltration of CD8

Indexed as

CD8-Positive T-LymphocytesGalectinsMicroRNAsStomach NeoplasmsAnimalsCell Line, TumorDisease ProgressionFemaleGene Expression Regulation, NeoplasticHumansMaleMiceGalectinsLGALS9 protein, humanMicroRNAsgastric cancerimmunosuppressionLGALS9miR‐491‐5pT cell

Identifiers

PMID41171621
PMCPMC12775568

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.