Evidence map›Paper›PMID 41171561›Full record

ReviewAdvances in experimental medicine and biology2025

Similarities and Differences in Genetics.

Wangyue Liu, Liping Yang, Hang Zhou, Xingguang Luo, Shiqiu Meng, Yan Sun, Jie Shi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wangyue LiuNational Institute on Drug Dependence, and Beijing Key Laboratory of Drug Dependence, Peking University, Beijing, China.
Liping YangNational Institute on Drug Dependence, and Beijing Key Laboratory of Drug Dependence, Peking University, Beijing, China.
Hang ZhouDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Xingguang LuoDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Shiqiu MengNational Institute on Drug Dependence, and Beijing Key Laboratory of Drug Dependence, Peking University, Beijing, China.
Yan SunNational Institute on Drug Dependence, and Beijing Key Laboratory of Drug Dependence, Peking University, Beijing, China. sunyan@bjmu.edu.cn.
Jie ShiNational Institute on Drug Dependence, and Beijing Key Laboratory of Drug Dependence, Peking University, Beijing, China. shijie@bjmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Partial pathogenesis is shared in substance- and nonsubstance-related addictions (e.g., pathological gambling, Internet addiction, binge-eating disorder) due to similar symptomatology and high co-morbidity. Genetics contributes to over 50% of vulnerability to substance addiction and plays a crucial role at each stage. Monoamine neurotransmitter system genes, including dopamine (DA), 5-hydroxytryptamine/serotonin (5-HT), and the endogenous opioid system, are suggested to be related to both substance and non-substance addictions. A systematic comparison of genetic mechanisms between non-substance addiction and substance addiction is necessary to reveal their essential biological similarities and differences. Thus, we conducted a review of the genetic similarities and differences between substance and non-substance addictions, aiming to enhance our understanding of addiction mechanisms and improve the clinical translation of addiction genetic findings.

Indexed as

Behavior, AddictiveSubstance-Related DisordersAnimalsDopamineGamblingGenetic Predisposition to DiseaseHumansDopamineDifferencesGeneticsNon-substance addictionSimilaritiesSubstance addiction

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.