Similarities and Differences in Neurobiology.

Shiqiu Meng, Yan Zhang, Nicholas J Beacher, Craig T Werner, Yan Sun, Jie Shi

Abstract readReview

In one paragraph

Review in Advances in experimental medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shiqiu MengNational Institute on Drug Dependence, and Beijing Key Laboratory of Drug Dependence, Peking University, Beijing, China.

Yan ZhangNational Institute on Drug Dependence, and Beijing Key Laboratory of Drug Dependence, Peking University, Beijing, China.

Nicholas J BeacherIntramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA.

Craig T WernerNational Center for Wellness and Recovery, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.

Yan SunNational Institute on Drug Dependence, and Beijing Key Laboratory of Drug Dependence, Peking University, Beijing, China.

Jie ShiNational Institute on Drug Dependence, and Beijing Key Laboratory of Drug Dependence, Peking University, Beijing, China. shijie@bjmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Substance addiction is a chronic, relapsing brain disease characterized by compulsive drug seeking and use despite harmful consequences. Non-substance addiction has recently been defined as compulsive engagement in non-drug-related rewarding activities (e.g., gambling) despite negative consequences. Although differences exist with respect to addictive objects, substances, and non-substance, addictions may share overlapping biological, epidemiological, clinical, and genetic features. Studies have shown that brain circuitry, as well as dopamine, serotonin, opioid, glutamate, and norepinephrine systems in the brain, is involved in both substance and non-substance addictions, but their specific contributions are debated. Here, we review the currently known overlapping and distinct neurotransmitter systems associated with these two types of addictions.

Indexed as

Behavior, AddictiveBrainNeurobiologyNeurotransmitter AgentsSubstance-Related DisordersAnimalsHumansNeurotransmitter AgentsNeurobiologyNon-substance addictionSubstance addiction

Identifiers

PMID41171560

DOI10.1016/j.biopsych.2007.06.008

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.