Evidence map›Paper›PMID 41171516›Full record

ArticleInfection2026

Fecal microbiota composition and clinical characteristics of patients with carbapenem-resistant enterobacterales colonization vs. patients with spontaneous decolonization.

O Lima, S Pérez-Castro, C Davina-Nunez, M Represa, P Rubiñán, M Ávila-Nuñez, A Filgueira, C Portela, B Sopeña, M T Pérez-Rodríguez

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Article in Infection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

O LimaInfectious Diseases Unit. Internal Medicine Department, Complexo Hospitalario Universitario de Pontevedra, Pontevedra, Spain. olalla.lima@gmail.com.
S Pérez-CastroGalicia Sur Health Research Institute (IIS Galicia Sur). SERGAS-UVIGO, Vigo, Spain. Sonia.Maria.Perez.Castro@sergas.es.
C Davina-NunezGalicia Sur Health Research Institute (IIS Galicia Sur). SERGAS-UVIGO, Vigo, Spain.
M RepresaInfectious Diseases Unit. Internal Medicine Department, Complexo Hospitalario Universitario de Pontevedra, Pontevedra, Spain.
P RubiñánGalicia Sur Health Research Institute (IIS Galicia Sur). SERGAS-UVIGO, Vigo, Spain.
M Ávila-NuñezInfectious Diseases Unit. Internal Medicine Department, Complexo Hospitalario Universitario de Vigo (CHUVI), Sergas, Vigo, Spain.
A FilgueiraVascular Surgery Department, Complexo Hospitalario Universitario de Pontevedra, Pontevedra, Spain.
C PortelaMicrobiology Department, Complexo Hospitalario Universitario de Vigo (CHUVI), Sergas, Vigo, Spain.
B SopeñaMedicine Department, University of Santiago de Compostela, Santiago, Spain.
M T Pérez-RodríguezGalicia Sur Health Research Institute (IIS Galicia Sur). SERGAS-UVIGO, Vigo, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCarbapenem-resistant Enterobacterales (CRE) intestinal colonization is a key risk factor for subsequent infection. The composition of the intestinal microbiota is likely to play a role in the colonization. The aim of the study was to compare the gut microbiota composition between colonised (Col) patients and decolonised (DeCol) patients.

methodsPatients were identified from a database of CRE colonised patients. They were categorized as either currently Col or having spontaneously DeCol. Baseline characteristics and survival in the following year after the gut microbiota characterization were also collected. Gut microbiota composition was analysed.

resultsA total of 37 patients were included: 14 in the Col group and 23 in the DeCol group. No significant differences in terms of age, BMI, sex, KATZ index, toxics, diet and comorbidity were observed. Previous hospital admission and infections caused by CRE and/or other microorganisms were more frequent in the Col group. During the 12-month follow-up, mortality was higher in the Col group (Col 43% vs. DeCol 9%, p = 0.035). Differences in beta diversity were observed according to Col status (Bray Curtis distance, PERMANOVA, p = 0.013) but not according to recent antibiotic treatment or hospital admission. Suterella, Roseburia faecis and Eubacterium ventriosumwere enriched in DeCol patients. CRE colonisation was associated with a higher abundance of Ruthenibacterium lactatiformans.

conclusionsThe composition of faecal microbiota was different between patients with ongoing CRE colonisation and those who achieved decolonisation. Further studies are needed to assess if specific bacterial taxa could be a marker of a longer colonisation risk.

Indexed as

Carbapenem-Resistant EnterobacteriaceaeEnterobacteriaceae InfectionsFecesGastrointestinal MicrobiomeAdultAgedAged, 80 and overAnti-Bacterial AgentsFemaleHumansMaleMiddle AgedAnti-Bacterial AgentsCarbapenem-resistantEubacteriumGut carriageMicrobiotaOXA-48-type

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.