Evidence map›Paper›PMID 41171476›Full record

ArticleMikrochimica acta2025

Online solid-phase extraction of glucoraphanin and sulforaphane from non-edible plants based on amino acid-functionalized covalent organic frameworks.

Yingchao Lv, Rongyu Wang, Tao Li, Heli Cheng, Ibragimov Aziz Bakhtiyarovich, Adizov Bobirjon Zamirovich, Iftikhar Ali, Wenhua Ji

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Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yingchao LvKey Laboratory for Natural Active Pharmaceutical Constituents Research, Universities of Shandong Province, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250014, China.
Rongyu WangKey Laboratory for Natural Active Pharmaceutical Constituents Research, Universities of Shandong Province, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250014, China.
Tao LiKey Laboratory for Natural Active Pharmaceutical Constituents Research, Universities of Shandong Province, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250014, China.
Heli ChengShandong C.P. Freda Pharmaceutical Co., Ltd., Jinan, 250100, China.
Ibragimov Aziz BakhtiyarovichInstitute of General and Inorganic Chemistry, Uzbekistan Academy of Sciences, 100170, Tashkent, Uzbekistan.
Adizov Bobirjon ZamirovichInstitute of General and Inorganic Chemistry, Uzbekistan Academy of Sciences, 100170, Tashkent, Uzbekistan.
Iftikhar AliDepartment of Chemistry, Karakoram International University, Gilgit, 15100, Pakistan.
Wenhua JiKey Laboratory for Natural Active Pharmaceutical Constituents Research, Universities of Shandong Province, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250014, China. jwh519@163.com.

Funding

People's livelihood Special Projects of Jinan 202317008Science, Education and Industry Integration Innovation Pilot Project from Qilu University of Technology (Shandong Academy of Sciences) 2025ZDZX07Taishan Scholars Program of Shandong Province tsqn202306252
6 · The paper itself

Abstract

Glucoraphanin (GR) and sulforaphane (SFN) are sulfur-containing compounds with diverse medicinal applications. However, cruciferous vegetables are a single source of GR and SFN, which limits development and utilization in natural resources. Herein, amino acid covalent organic framework (COF-Cys) was synthesized via click reactions and employed as an adsorbent in online solid-phase extraction (online SPE) to determine GR and SFN in non-edible plant samples. The adsorption mechanism was analyzed using density functional theory, revealing that adsorption occurred via electrostatic interaction and hydrogen bonding. Under the optimum conditions, good linearity (4-2500 ng/mL; R

Indexed as

Amino AcidsGlucosinolatesImidoestersIsothiocyanatesMetal-Organic FrameworksSolid Phase ExtractionAdsorptionLimit of DetectionOximesSulfoxidesTandem Mass SpectrometryVegetablesAmino AcidsglucoraphaninGlucosinolatesImidoestersIsothiocyanatesMetal-Organic FrameworksOximessulforaphaneSulfoxides, Covalent organic frameworks,Non edible plants,Sulforaphane,Ultra high performance liquid chromatography–tandem mass spectrometry

Identifiers

PMID41171476

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.