Angiogenesis and lymphangiogenesis in primary cutaneous lymphomas: a narrative review.

Mario Della Mura, Joana Sorino, Gerardo Cazzato, Giuseppe Ingravallo, Alessio Giubellino, Domenico Ribatti

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In one paragraph

Review in Clinical and experimental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Mario Della Mura *Section of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124, Bari, Italy.

Joana Sorino *Section of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124, Bari, Italy.

Gerardo CazzatoSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124, Bari, Italy.

Giuseppe IngravalloSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124, Bari, Italy.

Alessio GiubellinoDepartment of Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, MN, 55455, USA.

Domenico RibattiDepartment of Translational Biomedicine and Neuroscience, University of Bari Medical School, Bari, Italy. domenico.ribatti@uniba.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiogenesis and lymphangiogenesis are hallmarks of cancer and widely investigated both in solid and hematologic malignancies, correlating with tumor aggressiveness and progression. To date, the meaning of angiogenesis in primary cutaneous lymphomas has not been fully clarified, with most data coming from T cell lymphomas, in particular mycosis fungoides. Herein, we provide a comprehensive review about their significance in both primary cutaneous T cell and B cell lymphomas, with the aim to deepen the underlying molecular mechanism and role in tumor development and progression.

Indexed as

LymphangiogenesisLymphoma, B-CellLymphoma, T-Cell, CutaneousNeovascularization, PathologicSkin NeoplasmsAngiogenesisHumansAngiogenesisB cell lymphomaLymphangiogenesisMicrovessel densityMycosis fungoidesPrimary cutaneous lymphomaT cell lymphoma

Identifiers

PMID41171472

DOI10.1007/s10238-025-01853-2

PMCPMC12578752

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.