Evidence map›Paper›PMID 41171463›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2025

Bio-resorbable poly-4-hydroxybutyrate (P4HB) mesh for abdominal wall reconstruction is effective in high-risk patients and contaminated abdomen.

Anil K Srivastava, Katherine A Kummer, Bryan R Troop, Alison J Gildehaus, Kulsoom Gunn, Gina Davis

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Article in Hernia : the journal of hernias and abdominal wall surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anil K SrivastavaDepartment of Surgery, Division of Trauma and Acute Care Surgery, Mercy Hospital, 621 S. New Ballas Rd., St. Louis, MO, 63141, USA. anil.srivastava@mercy.net.
Katherine A KummerDepartment of Surgery, Division of Trauma and Acute Care Surgery, Mercy Hospital, 621 S. New Ballas Rd., St. Louis, MO, 63141, USA.
Bryan R TroopDepartment of Surgery, Division of Trauma and Acute Care Surgery, Mercy Hospital, 621 S. New Ballas Rd., St. Louis, MO, 63141, USA.
Alison J GildehausDepartment of Surgery, Division of Trauma and Acute Care Surgery, Mercy Hospital, 621 S. New Ballas Rd., St. Louis, MO, 63141, USA.
Kulsoom GunnDepartment of Surgery, Division of Trauma and Acute Care Surgery, Mercy Hospital, 621 S. New Ballas Rd., St. Louis, MO, 63141, USA.
Gina DavisDepartment of Surgery, Division of Trauma and Acute Care Surgery, Mercy Hospital, 621 S. New Ballas Rd., St. Louis, MO, 63141, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAbdominal wall reconstruction in patients with high-risk comorbidities and contamination is controversial. There is no standardized mesh choice for such clinical circumstances. We reviewed our experience of poly-4-hydroxybutyrate (P4HB) mesh for abdominal wall reconstruction in hostile abdomen after emergency and elective abdominal surgeries.

methodsWe performed a retrospective review of 48 patients with CDC class 3 or 4 contamination and high-risk comorbidities who underwent abdominal wall reconstruction with P4HB between June 2016-October 2019. Data collected included demographics, abdominal closure techniques, and long-term surgical site complications and hernia recurrence.

resultsPatients ranged from 33-88 years old; 70% were female. BMI ranged from 14-70 kg/m

conclusionP4HB mesh is well tolerated and provides durable abdominal wall reconstruction with acceptable hernia recurrence after emergency and elective abdominal closure, making it a sensible option for abdominal closure in high-risk comorbidities and abdominal contamination.

Indexed as

Abdominal WallAbdominal Wound Closure TechniquesAbsorbable ImplantsHernia, VentralHerniorrhaphyHydroxybutyratesPolyestersSurgical MeshSurgical Wound InfectionAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedHydroxybutyratesPolyestersAbdominal wall reconstructionContaminated abdomenHigh-risk comorbiditiesPoly-4-hydroxybutyrate mesh

Identifiers

PMID41171463

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.