Evidence map›Paper›PMID 41171433›Full record

ReviewEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Abiotrophia defectiva spondylodiscitis: case report and literature review.

Fabrizio Russo, Giuseppe Francesco Papalia, Paolo Brigato, Domenico Franco, Luca Ambrosio, Alice Laudisio, Gianluca Vadalà, Rocco Papalia, Vincenzo Denaro

Abstract readReview
PubMed Publisher
In one paragraph

Review in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fabrizio RussoResearch Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, Roma, 00128, Italy.
Giuseppe Francesco PapaliaResearch Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, Roma, 00128, Italy. g.papalia@policlinicocampus.it.ORCID http://orcid.org/0000-0002-4140-738X
Paolo BrigatoResearch Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, Roma, 00128, Italy.
Domenico FrancoResearch Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, Roma, 00128, Italy.
Luca AmbrosioResearch Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, Roma, 00128, Italy.
Alice LaudisioResearch Unit of Geriatrics, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21, Roma, 00128, Italy.
Gianluca VadalàResearch Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, Roma, 00128, Italy.
Rocco PapaliaResearch Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, Roma, 00128, Italy.
Vincenzo DenaroResearch Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, Roma, 00128, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSpondylodiscitis is a common infection affecting the intervertebral disc and represents a major concern in the field of spine surgery. Abiotrophia defectiva (AD) is part of the nutritionally variant streptococci, which are well acknowledged, although rare, species of streptococci. The aims of this study are to perform a literature review of vertebral infections from AD and present a case of spondylodiscitis after lumbar discectomy.

methodsAn electronic systematic search was conducted on PubMed and Scopus to select studies reporting spondylitis or discitis due to AD infection. Moreover, we report the first case of spondylodiscitis from AD infection after discectomy in a patient without medical history of dental procedures nor contemporary or subsequent development of cardiac valve infection.

resultsAD is a rare cause of vertebral infection, with only 4 cases described in literature, three of which in patients with an history of heart disease. The outcome is usually positive with vigorous antibiotic therapy, despite common difficulty in settling upon the proper antibiotic treatment. All the cases recovered as expected and didn't develop any serious long term sequalae from the infection.

conclusionDiscitis caused by AD are very rare events and are often caused by bacteremia with heart valve infection, dental infections, or dental procedures in patients with poor dental hygiene. The case we report highlights the combination of an infrequent pathology and an unusual pathogen for discitis. Moreover, this is the first case described in the literature of AD spondylodiscitis without a concomitant predisposing condition.

Indexed as

Abiotrophia defectivaCase reportLiterature reviewSpondylodiscitis

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.