Evidence map›Paper›PMID 41171410›Full record

ArticleMikrochimica acta2025

A novel molecularly imprinted sensor based on MOF-on-MOF architecture and Au nanoparticles for high-sensitivity electrochemical sensing of metformin.

Xin Zhang, Shuang Han, Yuan Wang, Chen Yan, Jiaying Yu, Xiaoyao Xie, Jiayi Song, Hongtao Chu, Wei Zong

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xin ZhangCollege of Chemistry and Chemical Engineering, Qiqihar University, Qiqihar, 161006, China.
Shuang HanCollege of Chemistry and Chemical Engineering, Qiqihar University, Qiqihar, 161006, China. iamhanshuang1982@163.com.
Yuan WangHeilongjiang Province Qiqihar Ecological Environment Monitoring Center, Qiqihar, 161005, China.
Chen YanCollege of Chemistry and Chemical Engineering, Qiqihar University, Qiqihar, 161006, China.
Jiaying YuCollege of Chemistry and Chemical Engineering, Qiqihar University, Qiqihar, 161006, China.
Xiaoyao XieCollege of Chemistry and Chemical Engineering, Qiqihar University, Qiqihar, 161006, China.
Jiayi SongCollege of Chemistry and Chemical Engineering, Qiqihar University, Qiqihar, 161006, China.
Hongtao ChuCollege of Chemistry and Chemical Engineering, Qiqihar University, Qiqihar, 161006, China.
Wei ZongCollege of Chemistry and Chemical Engineering, Qiqihar University, Qiqihar, 161006, China.

Funding

Ecological Environment Protection Project of Heilongjiang Province HST2023QT002Heilongjiang Provincial Foundation for the Characteristic Discipline of Processing Technology of Plant Foods YSTSXK202402Heilongjiang Provincial Natural Science Foundation of China LH2024E127Innovation Incentive Project of Qiqihar Technology Program CSFGG-2025153National Natural Science Foundation of China 22407068Program for Young Talents of Basic Research in Universities of Heilongjiang Province YQJH2023101the Fundamental Research Funds in Heilongjiang Provincial Universities 135409101
6 · The paper itself

Abstract

A novel metal-organic framework (MOF) supported Au nanoparticles (AuNPs)-based molecular imprinted electrochemical sensor (Au-MIECS) has been designed specifically for the detection of metformin (MET). Coupling different MOFs to form MOF-on-MOF structures can provide atomic charge transport channels, promote directional charge transfer and enhance electrochemical performance. To our knowledge, a combination of MOF-on-MOF and MIECS has not been reported. This is the first report on the preparation of MIECS based on MOF-on-MOF architecture. The synergistic effect of high electrical conductivity of AuNPs and the specificity of imprinting sites achieved excellent recognition to MET . The designed ultra-sensitive electrochemical sensor showed rapid response, excellent selectivity and wide linear range of 0.005-80 μM with a low detection limit of 1.911 nM.

Indexed as

Au nanoparticlesElectrochemical sensorMetforminMOF-on-MOFMolecular imprinting

Identifiers

PMID41171410

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.