ArticleJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2026
BMI and Breast Subcutaneous Fat: Potential Indicators for Ultrasound Diagnosis of Breast Cancer?
Article in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesObesity is closely associated with the occurrence and progression of breast cancer. While body mass index (BMI) is widely used to diagnose obesity, it has certain limitations. Subcutaneous fat thickness (SFT) also serves as an indicator of body composition. However, studies on breast SFT are scarce. This study aims to investigate the relationship between BMI, breast SFT, and ultrasound features of breast cancer, as well as their associations with tumor proliferation and invasiveness.
methodsThis study retrospectively analyzed the relationship between BMI and clinical and ultrasound characteristics in 1670 patients. Among them, breast SFT was measured in 470 patients using mammography and ultrasound, and the correlation between SFT and BMI was assessed. The relationship between ultrasound-measured SFT and pathological as well as ultrasound features was also analyzed. The correlation between breast SFT, BMI, and somatic gene mutations was analyzed in 234 patients.
resultsPatients with BMI ≥24 kg/m
conclusionsBMI and breast SFT are associated with malignant ultrasound features. While both have diagnostic value, BMI is more reliable than fat thickness for predicting cancer proliferation and invasion, with a BMI threshold of 22 kg/m
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