ArticleNucleic acids research2026
theRNA: a curated knowledgebase of functional RNA therapeutics spanning diverse modalities and disease applications.
Article in Nucleic acids research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- The 2026 Nucleic Acids Research database issue and the online molecular biology database collection.Nucleic acids research · 2026Article
- Target, silence, replace: a review on RNA-based drugs in modern medicine.Frontiers in cell and developmental biology · 2026Review
- The regulatory mechanisms and clinical translation potential of RNA-binding protein RALY in tumors.Frontiers in oncology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
RNA therapeutics are transforming precision medicine, yet a dedicated resource for validated agents has been lacking. Here, we introduce theRNA (https://therna.renlab.cn/), the first comprehensive database of 6860 experimentally validated RNA therapeutics targeting 1310 diseases in human or animal models. Curated from 11 126 peer-reviewed studies, theRNA focuses exclusively on functional therapeutic RNAs, including messenger RNA, small interfering RNA, microRNA, long noncoding RNA, circular RNA, short hairpin RNA, antisense oligonucleotides, aptamers, and CRISPR-related RNAs. Each entry provides extensive annotations on delivery modalities, efficacy readouts, and clinical potential. A user-friendly interface enables rapid searching and interactive exploration. As the first dedicated database for functional RNA therapeutics, theRNA aims to accelerate therapy development and deepen mechanistic understanding of disease and treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.