Evidence map›Paper›PMID 41171092›Full record

ArticleBiotechnology and bioengineering2026

Understanding the Role of pH Regulation and Neutralizing Agents in Organic Acid Production and Growth of Aspergillus oryzae.

Lukas Hartmann, Mark Christopher Martin, Anke Neumann, Dirk Holtmann, Katrin Ochsenreither

Erratum issuedAbstract read
In one paragraph

Article in Biotechnology and bioengineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. DualFoods (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Tempeh-type fermentation kinetics of tarwi (Frontiers in nutrition · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Lukas HartmannKarlsruhe Institute of Technology, Karlsruhe, Germany.ORCID 0000-0003-3357-6244
Mark Christopher MartinKarlsruhe Institute of Technology, Karlsruhe, Germany.
Anke NeumannKarlsruhe Institute of Technology, Karlsruhe, Germany.ORCID 0000-0002-9969-7586
Dirk HoltmannKarlsruhe Institute of Technology, Karlsruhe, Germany.
Katrin OchsenreitherUniversity of Applied Sciences Kaiserslautern, Pirmasens, Germany.ORCID 0000-0002-5797-2789

Funding

This study was supported by the Federal Ministry of Food and Agriculture (FKZ No.: 2220NR272A).
6 · The paper itself

Abstract

With growing interest in the valorization of renewable resources, the microbial production of organic acids using Aspergillus oryzae has gained attention. However, process parameters such as pH and neutralizing agents remain insufficiently understood. We investigated the effect of pH and different neutralizers on the production of malic, succinic, fumaric, pyruvic and citric acid and fungal growth using offline sampling and online monitoring of respiratory activity. Neutralizers included NaOH, Na

Indexed as

Aspergillus oryzaeCarboxylic AcidsHydrogen-Ion ConcentrationMalatesCarboxylic AcidsMalatesmalic acidmalic acidneutralizing agentorganic acidpH controlpH levelrespiratory activity

Identifiers

PMID41171092
PMCPMC12699135

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.