Evidence map›Paper›PMID 41171059›Full record

ArticlemBio2025

Small RNAs positively and negatively control transcription elongation through modulation of Rho utilization site accessibility.

Kristen R Farley, Andrew K Buechler, Colleen M Bianco, Carin K Vanderpool

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Bacterial small regulatory RNAs.Nature reviews. Microbiology · 2026
    Review
  2. Review
  3. TheJournal of bacteriology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kristen R FarleyDepartment of Microbiology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.ORCID 0000-0002-0677-7895
Andrew K BuechlerDepartment of Microbiology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.
Colleen M BiancoDepartment of Microbiology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.
Carin K VanderpoolDepartment of Microbiology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.ORCID 0000-0002-2850-5532

Funding

Small RNA Regulation in BacteriaR35GM139557 · NIGMS · UNIVERSITY OF MINNESOTA · PI Carin K Vanderpool · 2021 to 2026
$2.6M
National Science Foundation 2022049NIGMS NIH HHS R35 GM139557
6 · The paper itself

Abstract

Bacteria use a multi-layered regulatory strategy to precisely and rapidly tune gene expression in response to environmental cues. Small RNAs (sRNAs) form an important layer of gene expression control and most act post-transcriptionally to control translation and stability of mRNAs. We have shown that at least five different sRNAs (RydC, CpxQ, ArrS, GcvB, and OxyS) in

Indexed as

Escherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialRho FactorRNA, BacterialRNA, Small UntranslatedTranscription, Genetic5' Untranslated RegionsBinding SitesRNA, MessengerTranscription Termination, Genetic5' Untranslated RegionsEscherichia coli ProteinsRho FactorRho protein, E coliRNA, BacterialRNA, MessengerRNA, Small UntranslatedHfqRNase Esmall RNAtermination

Identifiers

PMID41171059
PMCPMC12691595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.