Evidence map›Paper›PMID 41171056›Full record

ArticlemSystems2025

Ziyun Li, Jiamin Hu, Yingmiao Pan, Yaxuan Xi, Lei Zhang

Abstract read
In one paragraph

Article in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ziyun LiMicrobiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID 0009-0005-1327-3168
Jiamin HuState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
Yingmiao PanMicrobiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yaxuan XiMicrobiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Lei ZhangMicrobiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID 0000-0003-4284-2604

Funding

Department of Science and Technology of Shandong Province ZR2022QC169
6 · The paper itself

Abstract

Early administration of antibiotics in children may heighten the susceptibility to multidrug-resistant bacterial infections. While probiotics are commonly employed for bacterial infection management, their nuanced advantages, particularly in curtailing the spread of antimicrobial resistance (AMR), remain unclear. This study investigated the role and mechanisms of IMPORTANCE: The global spread of antimicrobial resistance (AMR) has become a significant threat to public health, particularly in children, where the overuse of antibiotics leads to gut microbiota imbalance and increases the risk of horizontal transfer of antibiotic resistance genes (ARGs). This study supplemented mice with

Indexed as

Bifidobacterium longum subspecies infantisDrug Resistance, BacterialGastrointestinal MicrobiomeProbioticsAnimalsAnti-Bacterial AgentsBile Acids and SaltsEscherichia coliFecesGene Transfer, HorizontalHumansMiceTaurochenodeoxycholic AcidTaurocholic AcidAnti-Bacterial AgentsBile Acids and SaltsTaurochenodeoxycholic AcidTaurocholic Acidantimicrobial resistanceBifidobacterium infantisbile acidsgut microbiotahorizontal gene transfer

Identifiers

PMID41171056
PMCPMC12625698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.