Evidence map›Paper›PMID 41170977›Full record

ArticlemBio2025

Dual transcriptomic profiling of

Begoña García, Aritza Conty, Amaya Fernández-Celis, Daniel Mouzo, Carmen Gil, Nahiara Garmendia-Antoñana, Ana Navascues, Carmen Ezpeleta, Cristina Solano, Ivan Pasquier and 5 more

Erratum issuedAbstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Begoña GarcíaLaboratory of Microbial Pathogenesis, Navarrabiomed-Hospital Universitario de Navarra (HUN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Navarre, Spain.
Aritza Conty *Translational Cardiology Laboratory, Navarrabiomed-Hospital Universitario de Navarra (HUN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Navarre, Spain.
Amaya Fernández-Celis *Translational Cardiology Laboratory, Navarrabiomed-Hospital Universitario de Navarra (HUN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Navarre, Spain.
Daniel Mouzo *Unit of Translational Bioinformatics, Navarrabiomed-Hospital Universitario de Navarra (HUN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Navarre, Spain.
Carmen GilLaboratory of Microbial Pathogenesis, Navarrabiomed-Hospital Universitario de Navarra (HUN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Navarre, Spain.
Nahiara Garmendia-AntoñanaLaboratory of Microbial Pathogenesis, Navarrabiomed-Hospital Universitario de Navarra (HUN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Navarre, Spain.
Ana NavascuesDepartment of Clinical Microbiology, Hospital Universitario de Navarra (HUN), Pamplona, Navarre, Spain.
Carmen EzpeletaDepartment of Clinical Microbiology, Hospital Universitario de Navarra (HUN), Pamplona, Navarre, Spain.
Cristina SolanoLaboratory of Microbial Pathogenesis, Navarrabiomed-Hospital Universitario de Navarra (HUN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Navarre, Spain.ORCID 0000-0002-6207-1766
Ivan PasquierTranslational Cardiology Laboratory, Navarrabiomed-Hospital Universitario de Navarra (HUN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Navarre, Spain.
Virginia ÁlvarezTranslational Cardiology Laboratory, Navarrabiomed-Hospital Universitario de Navarra (HUN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Navarre, Spain.
Rafael SádabaTranslational Cardiology Laboratory, Navarrabiomed-Hospital Universitario de Navarra (HUN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Navarre, Spain.
David GómezUnit of Translational Bioinformatics, Navarrabiomed-Hospital Universitario de Navarra (HUN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Navarre, Spain.
Natalia López-AndresTranslational Cardiology Laboratory, Navarrabiomed-Hospital Universitario de Navarra (HUN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Navarre, Spain.
Iñigo LasaLaboratory of Microbial Pathogenesis, Navarrabiomed-Hospital Universitario de Navarra (HUN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Navarre, Spain.ORCID 0000-0002-6625-9221

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the intricate interactions between IMPORTANCE: To gain a full understanding of how bacteria infect tissues, it is necessary to characterize both the bacteria and the tissue at the time of infection. However, this analysis is very complex because it involves obtaining infected tissue directly from patients and analyzing it with minimal processing to preserve the characteristics of the natural state of infection. In this study, we examined the gene expression profiles of replaced heart valves from patients with

Indexed as

Endocarditis, BacterialGene Expression ProfilingStaphylococcal InfectionsStaphylococcus aureusTranscriptomeAnimalsDisease Models, AnimalHeart ValvesHumansSwinedual RNA-seqendocarditishuman heart valvesStaphylococcus aureus

Identifiers

PMID41170977
PMCPMC12691691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.