Evidence map›Paper›PMID 41170973›Full record

ArticleJournal of virology2025

The La Crosse virus Gc head domain is a major determinant of infection and pathogenesis.

Ariana Dedvukaj, Nicole C Rondeau, Tamara J B Vázquez, Alejandro E Cristófalo, Molly V Durawa, Matthew C Lutchko, Kenneth A Stapleford

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Ariana DedvukajDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.
Nicole C RondeauDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.
Tamara J B VázquezCentro de Investigaciones en Bionanociencias (CIBON), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Alejandro E CristófaloCentro de Investigaciones en Bionanociencias (CIBON), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Molly V DurawaDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.
Matthew C LutchkoDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.
Kenneth A StaplefordDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0002-7796-2254

Funding

Mechanisms of alphavirus infectivity and adaptation - Resubmission - 1R01AI162774 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI Kenneth Stapleford · 2022 to 2026
$2.7M
NIAID NIH HHS R01 AI162774
6 · The paper itself

Abstract

How orthobunyaviruses establish infections and disseminate to cause disease is not well understood. In a previous study using the

Indexed as

Encephalitis, CaliforniaLa Crosse virusAnimalsCell LineDisease Models, AnimalHumansMiceMice, Inbred C57BLMice, KnockoutMutationNeuronsProtein DomainsVirulenceVirus Replicationhead domainLa Crosse virusorthobunyavirusvirus entry

Identifiers

PMID41170973
PMCPMC12645916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.