Evidence map›Paper›PMID 41170528›Full record

ArticleAPL bioengineering2025

Oligonucleotide surface attachment by tosylation for digital detection of microRNA using photonic resonator absorption microscopy.

Skye Shepherd, Joseph Tibbs, Seemesh Bhaskar, Zayd Bala, Takhmina Ayupova, Lucas D Akin, Weinan Liu, Marcia H Monaco, Sharon M Donovan, Brian T Cunningham

Abstract read
In one paragraph

Article in APL bioengineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zayd BalaDepartment of Economics, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Lucas D Akin
Marcia H MonacoDepartment of Food Science and Human Nutrition, University of Illinois, Urbana-Champaign, Urbana, Illinois 61801, USA.ORCID https://orcid.org/0000-0003-1677-7773
Brian T CunninghamHolonyak Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.ORCID https://orcid.org/0000-0002-9681-2104

Funding

Exosome separation and digital resolution detection of blood-based nucleic acid biomarkers for noninvasive therapeutic diagnostics in cancerR01EB029805 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CUNNINGHAM, BRIAN T., DEMIRCI, UTKAN · 2020 to 2023
$2.1M
Rapid, simple, and ultrasensitive quantitation of KRAS ctDNA at the point of care using CRISPR/Cas amplification and digital resolution biosensor microscopyR33CA272271 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CUNNINGHAM, BRIAN T., MANSFIELD, AARON SCOTT · 2023 to 2025
$1.0M
NCI NIH HHS R33 CA272271NIBIB NIH HHS R01 EB029805
6 · The paper itself

Abstract

DNA capture probes attached to surfaces are necessary for many biosensing assays for the specific detection of nucleic acid target sequences. In this work, we present a chemically mediated direct oligonucleotide-titanium dioxide bond for stable DNA surface immobilization on photonic crystal (PC) biosensors. We validated the DNA-TiO

Identifiers

PMID41170528
PMCPMC12571496

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.