Evidence map›Paper›PMID 41170498›Full record

ArticleACS sustainable chemistry & engineering2025

Sustainable Triacetic Acid Lactone Production from Sugarcane by Fermentation and Crystallization.

Sarang S Bhagwat, Marco Nazareno Dell'Anna, Yalin Li, Mingfeng Cao, Emma C Brace, Sunil S Bhagwat, George W Huber, Huimin Zhao, Jeremy S Guest

Abstract read
In one paragraph

Article in ACS sustainable chemistry & engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarang S BhagwatDOE Center for Advanced Bioenergy and Bioproducts Innovation (CABBI), University of Illinois Urbana-Champaign, 1206 W. Gregory Drive, Urbana, Illinois 61801, United States.ORCID https://orcid.org/0000-0002-2620-2829
Marco Nazareno Dell'AnnaDOE Center for Advanced Bioenergy and Bioproducts Innovation (CABBI), University of Illinois Urbana-Champaign, 1206 W. Gregory Drive, Urbana, Illinois 61801, United States.
Yalin LiDOE Center for Advanced Bioenergy and Bioproducts Innovation (CABBI), University of Illinois Urbana-Champaign, 1206 W. Gregory Drive, Urbana, Illinois 61801, United States.ORCID https://orcid.org/0000-0002-8863-4758
Mingfeng CaoDOE Center for Advanced Bioenergy and Bioproducts Innovation (CABBI), University of Illinois Urbana-Champaign, 1206 W. Gregory Drive, Urbana, Illinois 61801, United States.ORCID https://orcid.org/0000-0002-6750-3871
Emma C BraceDOE Center for Advanced Bioenergy and Bioproducts Innovation (CABBI), University of Illinois Urbana-Champaign, 1206 W. Gregory Drive, Urbana, Illinois 61801, United States.ORCID https://orcid.org/0000-0001-7797-2295
Sunil S BhagwatDepartment of Chemical Engineering, Institute of Chemical Technology, Nathalal Parekh Marg, Matunga, Mumbai, Maharashtra 400019, India.
George W HuberDOE Center for Advanced Bioenergy and Bioproducts Innovation (CABBI), University of Illinois Urbana-Champaign, 1206 W. Gregory Drive, Urbana, Illinois 61801, United States.ORCID https://orcid.org/0000-0002-7838-6893
Huimin ZhaoDOE Center for Advanced Bioenergy and Bioproducts Innovation (CABBI), University of Illinois Urbana-Champaign, 1206 W. Gregory Drive, Urbana, Illinois 61801, United States.ORCID https://orcid.org/0000-0002-9069-6739
Jeremy S GuestDOE Center for Advanced Bioenergy and Bioproducts Innovation (CABBI), University of Illinois Urbana-Champaign, 1206 W. Gregory Drive, Urbana, Illinois 61801, United States.ORCID https://orcid.org/0000-0003-2489-2579

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triacetic acid lactone (TAL) has the potential to serve as a bioderived platform chemical for commercial products including sorbic acid and recyclable polydiketoenamine plastics. In this study, we leveraged BioSTEAM to design, simulate, and evaluate (via techno-economic analysis, TEA, and life cycle assessment, LCA) TAL production from sugarcane. We experimentally characterized TAL solubility, calibrated solubility models, and designed a process to separate TAL from fermentation broths by crystallization. The biorefinery could produce TAL at a minimum product selling price (MPSP) of $3.73-5.86·kg

Indexed as

biorefinery design and sizingfinancial viabilitygreenhouse gas emissionslife cycle assessment (LCA)sweet sorghumtechno-economic analysis (TEA)titer−yield opportunity spacetriacetic acid lactone (TAL) solubilityuncertainty

Identifiers

PMID41170498
PMCPMC12570263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.