Evidence map›Paper›PMID 41170482›Full record

ArticleFrontiers in public health2025

The economic burden of anxiety and depression in Indonesia: evidence from a cross-sectional web panel survey.

Karen Arulsamy, Elmeida Effendy, Sarah Mardhiyah, Mustafa M Amin, M Surya Husada, Vita Camellia, Anne-Claire Stona, Eric Andrew Finkelstein

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Family Honor, Gender Norms, and Help-Seeking Shape Mental Health Stigma in Saudi Arabia: A Systematic Review.Inquiry : a journal of medical care organization, provision and financing
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karen ArulsamyLien Centre for Palliative Care, Duke-NUS Medical School, Singapore, Singapore.
Elmeida EffendyDepartment of Psychiatry, Universitas Sumatera Utara, Medan, Indonesia.
Sarah MardhiyahDepartment of Psychiatry, Universitas Sumatera Utara, Medan, Indonesia.
Mustafa M AminDepartment of Psychiatry, Universitas Sumatera Utara, Medan, Indonesia.
M Surya HusadaDepartment of Psychiatry, Universitas Sumatera Utara, Medan, Indonesia.
Vita CamelliaDepartment of Psychiatry, Universitas Sumatera Utara, Medan, Indonesia.
Anne-Claire StonaSingHealth-Duke Global Health Institute, Duke-NUS Medical School, Singapore, Singapore.
Eric Andrew FinkelsteinLien Centre for Palliative Care, Duke-NUS Medical School, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mental health conditions are the second leading cause of disability in Indonesia, accounting for 13 percent of total years lived with disability. However, little is known about their broader economic impact. This study estimates the economic burden of anxiety and depression in adults, including healthcare costs and productivity losses, using a low-cost web panel approach that can be replicated in countries lacking data. Methods: A cross-sectional online survey was conducted with 5,828 Indonesian adults via a web panel. Participants completed the Patient Health Questionnaire-4 (PHQ-4) for themselves and household members, providing data on 16,096 individuals. Participants who screened positive for anxiety and/or depression symptoms based on the PHQ-4 (N = 438) were then asked about their healthcare utilization, days missed from work, and reduced productivity due to these symptoms. These responses were monetized and extrapolated based on the prevalence rate and population counts to generate per person and total annual costs. Results: Overall, 14.7 percent reported symptoms consistent with anxiety or depression, yet over 60 percent were never formally diagnosed, highlighting a large diagnosis gap. Direct healthcare costs averaged IDR 2,111,020 per person annually. Employees reported 34 missed workdays per year and were 51 percent less productive while working. Indirect costs via absenteeism and presenteeism averaged IDR 5,178,312 and IDR 11,021,700 per person. The total annual economic burden was IDR 463,811.33 billion (USD $29.22 billion), or 2.1 percent of Indonesia's GDP, with labor market productivity losses accounting for 88.5 percent of the total. Conclusion: Anxiety and depression impose substantial health and economic costs in Indonesia. Low-cost, evidence-based interventions-particularly workplace-focused programs-could generate significant health and economic benefits.

Indexed as

AnxietyCost of IllnessDepressionHealth Care CostsAdolescentAdultCross-Sectional StudiesFemaleHumansIndonesiaInternetMaleMiddle AgedPrevalenceSurveys and Questionnairesanxietycost-of-illnessdepressioneconomic burdenIndonesia

Identifiers

PMID41170482
PMCPMC12570936

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.