ArticleFrontiers in microbiology2025
Proteomic analyses of the regulatory mechanisms underlying
Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Results: In total, 4,293 differentially expressed proteins (DEPs) were identified, which were mainly involved in energy metabolism, protein synthesis and modification, oxidative stress, and other key biological processes. In the early stages of infestation, the fungus rapidly adapted to the host environment by enhancing metabolism and protein synthesis, initiating the infestation mechanism, and simultaneously enhancing its antioxidant capacity to cope with the host defense response. At later stages, it fine-tuned the metabolic pathways and enhanced DNA replication to maintain proliferation and continuously strengthened the antioxidant response to host oxidative stress. In addition, the number of proteins related to fungal transporter activity varied significantly after induction, indicating that a variety of transmembrane proteins may be involved in host recognition, adhesion, and formation of invasive structures. Conclusion: This study provides critical insights into the molecular mechanisms underlying
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