Evidence map›Paper›PMID 41170374›Full record

ReviewFrontiers in pharmacology2025

Mini review: Persister cell control strategies.

Mohamad Javad Hashemi, Yousr Dhaouadi Khattab, Dacheng Ren

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mohamad Javad HashemiDepartment of Biomedical and Chemical Engineering, Syracuse University, Syracuse, NY, United States.
Yousr Dhaouadi KhattabDepartment of Biomedical and Chemical Engineering, Syracuse University, Syracuse, NY, United States.
Dacheng RenDepartment of Biomedical and Chemical Engineering, Syracuse University, Syracuse, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial persisters are growth-arrested cells with low metabolic activities, but have no genetic mutations compared to their parental cells. The dormant nature of persister cells enables them to tolerate high doses of conventional antibiotics and restart growth after the antibiotic is withdrawn, posing an important challenge to infection control. To promote more research in this important area, we present a concise review of current persister control strategies and discuss future opportunities.

Indexed as

AI-driven drug discoveryantibioticantibiotic persistencecombination therapypersister bacteria

Identifiers

PMID41170374
PMCPMC12568461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.