Evidence map›Paper›PMID 41170348›Full record

ArticleJournal of medical cases2025

A Rare Co-Occurrence of Gastric Heterotopia and Autonomic Nervous System Dysfunction: An Attempt to Explain If There Is a Need to Explore Possible Syndromic Link.

Lana Alhalabi, Omar Alhalabi, Asad Khan, Jafer Ali, Prakash Gupta, Mohamed H Ahmed

Abstract readCase Reports
In one paragraph

Article in Journal of medical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lana AlhalabiMedical School, The University of Buckingham, Buckingham MK18 1EG, UK.
Omar AlhalabiMedical School, The University of Buckingham, Buckingham MK18 1EG, UK.
Asad KhanDepartment of Gastroenterology and Hepatology, Milton Keynes University Hospital NHS Foundation Trust, Eaglestone, Milton Keynes MK6 5LD, UK.
Jafer AliDepartment of Gastroenterology and Hepatology, Milton Keynes University Hospital NHS Foundation Trust, Eaglestone, Milton Keynes MK6 5LD, UK.
Prakash GuptaDepartment of Gastroenterology and Hepatology, Milton Keynes University Hospital NHS Foundation Trust, Eaglestone, Milton Keynes MK6 5LD, UK.
Mohamed H AhmedDepartment of Geriatric Medicine, Milton Keynes University Hospital NHS Foundation Trust, Eaglestone, Milton Keynes MK6 5LD, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric heterotopia (GHT) is the presence of gastric mucosa outside the stomach, including in the rectum. A 59-year-old man presented with rectal bleeding and altered bowel habits, along with long-standing low blood pressure and erectile dysfunction. Investigations confirmed rectal GHT, initially managed conservatively, followed by mucosectomy, which improved his gastrointestinal symptoms. However, persistent dizziness, blurred vision, and urinary symptoms prompted neurological evaluation, revealing autonomic nervous system (ANS) dysfunction. This case represents the first reported co-occurrence of GHT and ANS dysfunction. Although both conditions are rare and typically unrelated, their co-presentation suggests a possible link. We hypothesize that chronic inflammation or neurochemical signaling from ectopic gastric mucosa may contribute to autonomic disruption. Further research is needed to explore shared pathophysiological mechanisms.

Indexed as

Autonomic nervous system dysfunctionCongenital central hypoventilation syndromeFamilial dysautonomiaGastric heterotopiaHirschsprung disease

Identifiers

PMID41170348
PMCPMC12571122

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.