Evidence map›Paper›PMID 41170261›Full record

ArticleCureus2025

Inhaled Isopropyl Alcohol for Refractory Cannabis Hyperemesis Syndrome: A Case With Pneumomediastinum and Pneumothorax.

Abdul Rehman, Muhammad Ahmad Javed

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Abdul RehmanEmergency Department, St. Luke's General Hospital, Kilkenny, IRL.
Muhammad Ahmad JavedEmergency Department, St. Luke's General Hospital, Kilkenny, IRL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cannabis hyperemesis syndrome (CHS) is a well-recognized condition associated with chronic cannabis use, characterized by recurrent nausea, retching, vomiting, and relief with hot showers. Management is challenging, particularly as symptoms are refractory to conventional antiemetic therapy. We report the case of a 26-year-old man with a history of daily cannabis use who presented with severe retching and vomiting, complicated by pneumothorax and pneumomediastinum. His nausea and retching persisted despite multiple antiemetic therapies but responded rapidly to inhaled isopropyl alcohol (IPA) swabs. This case highlights the potential role of non-pharmacological aromatherapy as a safe and effective adjunct in managing refractory CHS while also underscoring the serious complications that can occur from severe persistent emesis.

Indexed as

boerhaave syndromecannabis hyperemesis syndromeconservative managementisopropyl alcoholpneumomediastinumrefractory vomitingspontaneous tracheal rupturesubcutaneous emphysemavomiting-induced injury

Identifiers

PMID41170261
PMCPMC12571059

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.