ArticleCureus2025
Descemet's Membrane Detachment Following Inadvertent Intrastromal Injection of an Ophthalmic Viscoelastic Device.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypotony is a well-documented postoperative complication of glaucoma filtration surgery. Management may include the injection of an ophthalmic viscoelastic device (OVD) into the anterior chamber. This case report describes a 45-year-old woman with juvenile-onset open-angle glaucoma who developed clinical hypotony after trabeculectomy surgery augmented with mitomycin-C. An intracameral injection of Healon5® (Johnson & Johnson Vision, USA) was attempted to restore physiological intraocular pressure (IOP); however, Healon5® was inadvertently introduced into the corneal stroma, causing a localised Descemet's membrane detachment (DMD). Following non-resolution with observation and attempted surgical evacuation, an intracameral air tamponade successfully addressed the DMD. An intracameral air tamponade may provide a quicker alternative to prolonged observation, particularly for highly cohesive OVDs such as Healon5®.
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