ArticleCureus2025
Apixaban-Induced Leukocytoclastic Vasculitis: An Uncommon Complication of a Common Anticoagulant.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Apixaban-induced leukocytoclastic vasculitis (LCV) is rare, with only a handful of cases reported. We describe a 68-year-old man who developed a diffuse, painful, pruritic rash and myalgias approximately six weeks after the initiation of apixaban. Extensive infectious and autoimmune workups were negative. Although the skin biopsy was nonspecific, corticosteroid therapy and apixaban discontinuation led to marked clinical improvement. The temporal association and exclusion of other causes support apixaban as the likely trigger. This case contributes to the growing recognition of apixaban-induced LCV and highlights the need to consider drug-induced etiologies in new-onset vasculitic rashes, especially in anticoagulated patients.
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Registered trials
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