Kuwait Heart Foundation Registry of Acute Coronary Events: Design and Rationale of Large Contemporary Registry of Acute Coronary Syndromes.

Aim: The aim of this study was to describe the design and rationale of a registry of patients with acute coronary syndromes (ACSs) in Kuwait. Methods: Kuwait Heart Foundation Registry of Acute Coronary Events (KHF RACEs) is a prospective, multicenter, observational, cohort-based registry of consecutive patients admitted to hospitals in Kuwait with a working diagnosis of ACSs. The trial is registered at "Clinical Trials.gov" number NCT05857735 and enrollment started on May 15, 2023. It involved 8 hospitals and 124 investigators. Data were collected prospectively and entered into an online system specifically created for this registry. This included demographic data, risk factors, past medical history, medications at admission and discharge, pertinent findings on physical examination at admission, inhospital investigations, and management including cardiac catheterization and subsequent percutaneous coronary interventions. The observed outcomes included inhospital and 30-day mortality and major adverse cardiac events. Conclusion: KHF RACE is the largest contemporary ACS registry in the Middle East. It provides an example of how large multicenter registries can be carried out successfully in this part of the world. Results are expected to shed light on the adherence to guidelines in our daily practice and its influence on patients' outcomes. Several analyses of the data are planned, including the influence of age, gender, diabetes, and insurance status on outcomes. Other planned analyses will be relating to cardiac catheterization and its related outcomes.