Evidence map›Paper›PMID 41170073›Full record

ArticleBioinformation2025

Molecular markers in triple-negative breast cancer: A retrospective correlation study.

Sudarshan Gupta, Purti Agrawal Saini, Vikas Pandey, Mitesh Shah

Abstract read
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sudarshan GuptaDepartment of Pathology, VKS Government Medical College, Neemuch, Madhya Pradesh, India.
Purti Agrawal SainiDepartment of Pathology, Nandkumar Singh Chouhan Government Medical College, Khandwa, Madhya Pradesh, India.
Vikas PandeyDepartment of Pathology, Government Medical College, Santa, Madhya Pradesh, India.
Mitesh ShahDepartment of Pathology, Bundelkhand Medical College, Sagar, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expression and clinical correlation of molecular markers in 128 patients diagnosed with triple-negative breast cancer (TNBC). Immunohistochemistry was used to assess markers including Ki-67, p53, EGFR and CK5/6. High Ki-67 and p53 positivity were significantly associated with higher tumor grade and lymph node involvement. EGFR and CK5/6 expression correlated with basal-like features and poor differentiation. Data suggest that molecular profiling in TNBC may guide prognosis and targeted therapies.

Indexed as

basal-like phenotypeCK5/6EGFRKi-67molecular markersp53Triple-negative breast cancer

Identifiers

PMID41170073
PMCPMC12569943

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.