Evidence map›Paper›PMID 41169984›Full record

ArticleHeart rhythm O22025

De novo pulmonary vein isolation in obese vs nonobese patients under deep sedation: Does obesity increase procedure complexity?

Vera Maslova, Marie Ahrens, Ole Rosenthal, Theodor Bau, Peter Magerfleisch, Fabian Moser, Adrian Zaman, Mohammed Saad, Martina Spehlmann, Derk Frank and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vera MaslovaDepartment of Internal Medicine III, Cardiology and Angiology, University Hospital Schleswig-Holstein, Kiel, Germany.
Marie AhrensDepartment of Internal Medicine III, Cardiology and Angiology, University Hospital Schleswig-Holstein, Kiel, Germany.
Ole RosenthalDepartment of Internal Medicine III, Cardiology and Angiology, University Hospital Schleswig-Holstein, Kiel, Germany.
Theodor BauDepartment of Internal Medicine III, Cardiology and Angiology, University Hospital Schleswig-Holstein, Kiel, Germany.
Peter MagerfleischDepartment of Internal Medicine III, Cardiology and Angiology, University Hospital Schleswig-Holstein, Kiel, Germany.
Fabian MoserDepartment of Internal Medicine III, Cardiology and Angiology, University Hospital Schleswig-Holstein, Kiel, Germany.
Adrian ZamanDepartment of Internal Medicine III, Cardiology and Angiology, University Hospital Schleswig-Holstein, Kiel, Germany.
Mohammed SaadDepartment of Internal Medicine III, Cardiology and Angiology, University Hospital Schleswig-Holstein, Kiel, Germany.
Martina SpehlmannDepartment of Internal Medicine III, Cardiology and Angiology, University Hospital Schleswig-Holstein, Kiel, Germany.
Derk FrankDepartment of Internal Medicine III, Cardiology and Angiology, University Hospital Schleswig-Holstein, Kiel, Germany.
Evgeny LianDepartment of Internal Medicine III, Cardiology and Angiology, University Hospital Schleswig-Holstein, Kiel, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary vein isolation (PVI) in obese patients under deep sedation (DS) is anticipated to be more complex owing to challenging airway and hemodynamic management and dose adjustment of sedation drugs. Objective: This study aimed to compare the complexity of de novo PVI in obese vs nonobese patients, with a particular focus on periprocedural sedation. Methods: All patients undergoing de novo PVI under DS between January 2022 and January 2024 in our center were prospectively included. Data on detailed monitoring of respiratory and hemodynamic parameters during the procedure were collected. Two groups were defined (group 1, body mass index [BMI] of ≥30 kg/m Results: Overall, 381 patients were included (61% male, median age 69 years); 120 were assigned to group 1 (BMI of 33 kg/m Conclusion: Obesity was not an independent risk factor for periprocedural hypoxia or hypotension and did not affect safety or long-term success. Obesity alone should not be considered a reason to exclude patients from undergoing PVI under DS.

Indexed as

Atrial fibrillationCatheter ablationCryoballoon ablationDeep sedationObesityPropofolPulsed field ablation

Identifiers

PMID41169984
PMCPMC12570196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.