Evidence map›Paper›PMID 41169963›Full record

ArticleHeart rhythm O22025

Pulsed-field ablation versus radiofrequency ablation in patients undergoing repeat catheter ablation for atrial fibrillation.

Corinne Isenegger, Gianluca Di Bari, Rebecca Arnet, Fabian Jordan, David Spreen, Behnam Subin, Philipp Krisai, Sven Knecht, Nicolas Schaerli, Gian Voellmin and 4 more

Abstract read
In one paragraph

Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Circulating miR-10b-5p as a candidate biomarker of atrial fibrillation recurrence after catheter ablation: a two-phase translational study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Corinne IseneggerDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
Gianluca Di BariDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
Rebecca ArnetDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
Fabian JordanDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
David SpreenDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
Behnam SubinDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
Philipp KrisaiDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
Sven KnechtDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
Nicolas SchaerliDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
Gian VoellminDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
Felix MahfoudDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
Christian SticherlingDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
Michael KühneDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
Patrick BadertscherDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulsed-field ablation (PFA) is noninferior compared with thermal energy sources such as radiofrequency ablation (RFA) or cryoballoon ablation for de novo pulmonary vein isolation (PVI). However, its potential value for repeat catheter ablation (CA) after unsuccessful thermal PVI has not been assessed. Objective: This study aimed to compare the procedural characteristics, safety, and efficacy between PFA and RFA in patients undergoing repeat CA after previous thermal PVI. Methods: Patients with recurrent atrial fibrillation (AF) undergoing repeat CA at a tertiary referral center were prospectively enrolled. All redo procedures were guided by a 3-dimensional electroanatomic mapping system and performed using either PFA or RFA. Results: A total of 185 patients underwent repeat CA for AF (median age 68 years [60-74], 31% female, 53% paroxysmal AF, and 47% persistent AF). PFA was used in 71 patients (38%), whereas RFA was used in 114 patients (62%). The median procedure time was similar between the PFA and RFA groups (61 minutes [50-71] vs 56 minutes [45-82] Conclusion: In patients undergoing repeat CA after thermal PVI, PFA resulted in similar procedural characteristics, safety, and arrythmia-free survival compared with RFA.

Indexed as

Atrial fibrillationCatheter ablationPulmonary vein isolationPulsed-field ablationRadiofrequency ablation

Identifiers

PMID41169963
PMCPMC12570212

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.