Evidence map›Paper›PMID 41169957›Full record

ArticleCase reports in dentistry2025

Root Development Following Bioceramic Material Application in Immature Permanent Teeth: A Case Series With 24-Month Follow-Up.

Yasser Alsayed Tolibah, Nada Bshara, Mohammad Tamer Abbara, Marwan Alhaji, Osama Aljabban, Ibrahim Ali Ahmad, Ziad D Baghdadi

Registry-linked trialAbstract readCase Reports
In one paragraph

Article in Case reports in dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06119477 (Comparison of Three Techniques in Bioceramic Apexification Procedure for Necrotic Immature Incisors), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06119477 nacompletednot on this map

Comparison of Three Techniques in Bioceramic Apexification Procedure for Necrotic Immature Incisors: A Randomized Clinical Trial

TypeinterventionalSponsorDamascus UniversityRan2023 to 2025Enrolled45ConditionsImmature Teeth, Periapical LesionArmsBioceramic Putty Apical Plugs, Single Cone Gutta-percha with Bioceramic Sealer, Combination of Bioceramic Putty and Sealer
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Epidemiology Meets Advocacy: Understanding Pediatric Dental Trauma and Delayed Care in Post-Conflict Syria.International journal of environmental research and public health · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yasser Alsayed TolibahDepartment of Pediatric Dentistry, Damascus University, Damascus, Syria.ORCID https://orcid.org/0000-0001-5498-9991
Nada BsharaDepartment of Pediatric Dentistry, Damascus University, Damascus, Syria.ORCID https://orcid.org/0000-0003-0055-6204
Mohammad Tamer AbbaraDepartment of Endodontics, Damascus University, Damascus, Syria.ORCID https://orcid.org/0000-0003-3664-0248
Marwan AlhajiDepartment of Pediatric Dentistry, Damascus University, Damascus, Syria.ORCID https://orcid.org/0009-0004-2014-309X
Osama AljabbanDepartment of Endodontics, Damascus University, Damascus, Syria.ORCID https://orcid.org/0000-0002-6175-6632
Ibrahim Ali AhmadDentistry Department, Al-Wakra Hospital, Hamad Medical Corporation, Doha, Qatar.ORCID https://orcid.org/0000-0002-0780-9414
Ziad D BaghdadiDivision of Pediatric Dentistry, Department of Preventive Dental Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID https://orcid.org/0000-0002-0071-9141

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Dental trauma frequently impacts children and adolescents, leading to functional and esthetic challenges. If not managed promptly and effectively, complications may ensue. Apexification with calcium silicate cement (CSC) has been proposed as a reliable treatment for necrotic immature teeth with thick dentinal walls and open apices. While CSC effectively eliminates periapical infection and improves tooth survival, its ability to promote root lengthening in immature teeth is not consistently proven. Materials and Methods: This case series highlights five instances in four children of traumatized anterior teeth with necrotic pulps treated using bioceramic putty and bioceramic sealer-a contemporary generation of CSC-in apexification procedures spanning two to three visits. Results: Radiographic follow-ups of 24 months demonstrated successful canal system sealing, periapical lesions healing, and notable root lengthening. Importantly, no posttreatment complications, such as pain or exacerbation, were observed, underscoring the efficacy and potential of these materials for managing necrotic immature permanent teeth. Conclusion: Bioceramic apical barrier is recognized as an effective treatment for managing traumatized anterior teeth. Moreover, it demonstrates promising results by facilitating the healing of necrotic immature teeth and potentially supporting root lengthening. Trial Registration: ClinicalTrials.gov identifier: NCT06119477.

Indexed as

apical barrierbioceramicsimmature teethperiapical healing

Identifiers

PMID41169957
PMCPMC12571529

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.