Evidence map›Paper›PMID 41169940›Full record

ArticleJournal of traditional and complementary medicine2025

Effectiveness of Zhengqing Fengtongning in combination with routine rheumatoid arthritis treatment: A real-world multicenter retrospective study.

Ze Yu, Zan Li, Ya Gao, Chunming Lyu, Fang Kou, Jialong Guo, Fei Gao, Hai Wei

Abstract read
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In one paragraph

Article in Journal of traditional and complementary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ze YuInstitute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Zan LiDepartment of Sports Medicine, Shenyang Orthopedic Hospital, Shenyang, 110000, China.
Ya GaoDepartment of Pharmacy, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing, 100037, China.
Chunming LyuInstitute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Fang KouInstitute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Jialong GuoDepartment of Rheumatology and Immunology, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, 130033, China.
Fei GaoBeijing Medicinovo Technology Co. Ltd., Beijing, 100071, China.
Hai WeiInstitute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Zhengqing Fengtongning (ZF) is a modern traditional Chinese medicine preparation used to treat rheumatoid arthritis (RA). In this study, we aimed to prove the effectiveness of ZF in combination with routine RA treatment in the real world. Methods: This was a retrospective study including 3877 RA patients in multi-centers from August 2015 to April 2023. The experimental group received ZF and the control group received other RA regimens. Propensity score matching was used to eliminate bias. The effectiveness of ZF in combination with routine RA treatment was evaluated through DAS28, ESR, CRP and RF. Results: The effectiveness of combining ZF with methotrexate (MTX), iguratimod (IGU), leflunomide (LEF), MTX + LEF, and MTX + nonsteroidal anti-inflammatory drugs in treating RA was significantly better than that of not combining ZF ( Conclusions: This study provides evidence that the effectiveness of MTX, IGU, LEF, MTX + LEF, and MTX + NSAIDs combined with ZF in treating RA was better than those without ZF.

Indexed as

Real-worldRheumatoid arthritisRoutine rheumatoid arthritis treatmentSinomenineZhengqing Fengtongning

Identifiers

PMID41169940
PMCPMC12570101

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.