Evidence map›Paper›PMID 41169891›Full record

ArticleFrontiers in pediatrics2025

Exploring long COVID in pediatric patients: clinical insights from a long COVID clinic.

Dina Kamel, My H Vu, Jeffery Bender, David Warburton, John C Wood, Sindhu Mohandas

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PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dina KamelDivision of Infectious Diseases, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, United States.
My H VuBiostatistics and Data Management Core, The Saban Research Institute, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, United States.
Jeffery BenderDivision of Infectious Diseases, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, United States.
David WarburtonDepartment of Pediatrics, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, United States.
John C WoodDepartment of Pediatrics, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, United States.
Sindhu MohandasDivision of Infectious Diseases, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Long COVID describes the persistence or recurrence of symptoms beyond the acute phase of SARS-CoV-2 infection and is increasingly recognized in children and adolescents. Despite its prevalence, understanding of symptom patterns and the influence of vaccination on disease trajectory in pediatric populations remains limited. Methods: We conducted a retrospective study of patients aged 0-21 years evaluated at the Long COVID Clinic at Children's Hospital Los Angeles between August 2021 and November 2023. Patients were included if they reported persistent or new symptoms ≥4 weeks after SARS-CoV-2 infection. Results: A total of 123 patients were enrolled. The mean age was 13.1 years, and 51% were male. Symptom onset occurred a mean of 5 weeks after infection. At presentation, 56% of patients reported symptoms lasting 0-24 weeks, 28% for 25-52 weeks, and 16% for >52 weeks. Fatigue (93%) and headache (70%) were the most prevalent symptoms in both younger (<12 years) and older (>12 years) cohorts. Female patients more frequently reported brain fog, dizziness, palpitations, and postural orthostatic tachycardia syndrome. Overall symptom burden decreased significantly over time ( Conclusion: Pediatric long COVID is marked by prolonged, multisystem symptoms. Vaccination may offer symptomatic benefit for some patients, though larger prospective studies are necessary to better define its role.

Indexed as

COVID-19COVID 19 vaccinelong COVIDPASCpost COVID

Identifiers

PMID41169891
PMCPMC12568432

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.