ArticleJournal of conservative dentistry and endodontics2025
Randomized clinical trial comparing bacterial reduction in primarily infected root canals using ProTaper Ultimate and ProTaper Next systems.
Article in Journal of conservative dentistry and endodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Effect of different rotary instrument designs (protaper ultimate and protaper gold) on postoperative pain and bacterial reduction: a randomized clinical trial.BMC oral health · 2026Trial
- Uncommon Canal Anatomy: Identification and Treatment of Middle Distal Canal in Mandibular First Molars-A Report on Two Cases.Case reports in dentistry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The successful outcome of endodontic therapy relies on effective debridement and disinfection of the root canal system. Mechanical instrumentation, with irrigation, remains the cornerstone for reducing microbial load within the complex root canals. ProTaper Ultimate is a recently introduced file system that promises effective bacterial load reduction from the root canal. Aim: The aim of the study was to compare the bacterial load reduction from primarily infected root canals using two rotary file systems, ProTaper Ultimate and ProTaper Next. Methods: Twenty-eight mandibular premolars with a single root and canal with necrotic pulp and asymptomatic apical periodontitis, requiring endodontic treatment, were selected and divided into two groups: Group A (ProTaper Ultimate), Group B (ProTaper Next). Cleaning and shaping of the canal was done in both the groups using 2.5% sodium hypochlorite as an irrigant. Colony-forming units measurements were used to assess the overall bacterial reduction (both aerobic and anaerobic) before and after instrumentation and the difference was calculated. Statistical Analysis: The normality of data distribution was assessed using the Kolmogorov-Smirnov and Shapiro-Wilk tests. Intragroup comparison was done using the Wilcoxon signed-rank test, and intergroup comparison using Mann-Whitney Results: There was no statistically significant difference ( Conclusion: ProTaper Ultimate is equally effective in reducing overall bacterial load as ProTaper Next in primarily infected root canals.
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Registered trials
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