ArticleJournal of conservative dentistry and endodontics2025
Clinical implications of apically extruded resin-based sealers: A long-term observation.
Article in Journal of conservative dentistry and endodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- In Vitro Assessment of Osteogenic Modulation and Molecular Responses Induced by Contemporary Endodontic Sealers in MC3T3-E1 Pre-Osteoblasts.Dentistry journal · 2026Article
- Foreign body-associated maxillary sinus aspergillosis caused by Endomethasone extrusion: diagnostic challenges, biological mechanisms, and surgical management.Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Apical extrusion of resin-based sealers is a common yet concerning event in root canal therapy, with uncertain effects on long-term periapical healing. This case series evaluates the clinical and radiographic outcomes of four cases with unintentional sealer extrusion, treated nonsurgically by a single operator using standardized protocols. All cases showed extrusion of resin-based sealer without gutta-percha overextension. Patients were followed for up to 3 years with periodic assessments. Despite the presence of extruded material, all cases exhibited favorable healing or healed status based on Strindberg's criteria, with no clinical symptoms reported. Although the volume of sealer appeared reduced over time, complete resorption was not observed. These findings suggest that apically extruded resin-based sealers may remain inert and do not necessarily compromise periapical healing. Further studies with larger sample sizes and advanced imaging modalities are recommended to validate these observations and explore outcomes with different sealer types.
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Registered trials
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