Evidence map›Paper›PMID 41169704›Full record

ReviewDrug design, development and therapy2025

Prospects and Challenges of Chitosan-Based Drug Carriers for Anticancer Agents' Delivery Against Lung Cancer: A Review.

Yan Liu, Baolian Yang, Hao Chen, Yumei Liao, Shiyu Zhang, Jianqiong Yang, Weiliang Chen, Hai Liu

Abstract readReview
In one paragraph

Review in Drug design, development and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yan Liu *Jiangxi Province Key Laboratory of Pharmacology of Traditional Chinese Medicine, College of Pharmacy, Gannan Medical University, Ganzhou, 341000, People's Republic of China.ORCID 0009-0001-2761-8842
Baolian Yang *Department of Manufacturing Laboratory, Ganzhou Hospital of Traditional Chinese Medicine, Ganzhou, 341000, People's Republic of China.
Hao ChenJiangxi Province Key Laboratory of Pharmacology of Traditional Chinese Medicine, College of Pharmacy, Gannan Medical University, Ganzhou, 341000, People's Republic of China.
Yumei LiaoInnovation and Translational Medicine Research Institute, Gannan Medical University, Ganzhou, 341000, People's Republic of China.
Shiyu ZhangInnovation and Translational Medicine Research Institute, Gannan Medical University, Ganzhou, 341000, People's Republic of China.
Jianqiong YangGanzhou Key Laboratory of Antitumor Effects of Natural Products, The First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, People's Republic of China.ORCID 0000-0002-9063-8117
Weiliang ChenJiangxi Province Key Laboratory of Pharmacology of Traditional Chinese Medicine, College of Pharmacy, Gannan Medical University, Ganzhou, 341000, People's Republic of China.ORCID 0009-0004-9448-4401
Hai LiuJiangxi Province Key Laboratory of Pharmacology of Traditional Chinese Medicine, College of Pharmacy, Gannan Medical University, Ganzhou, 341000, People's Republic of China.ORCID 0000-0002-1748-0990

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer remains one of the leading causes of cancer-related mortality and morbidity worldwide. Despite significant advancements in diagnostic techniques and therapeutic modalities such as surgery, chemotherapy, and radiotherapy, there is an urgent need for innovative therapeutic approaches due to severe adverse reactions, escalating multidrug resistance, an increased risk of tumor recurrence, and the complexity of the tumor microenvironment (TME). Nanotechnology-based drug delivery systems have emerged as a novel strategy for lung cancer treatment by enhancing drug targeting, reducing toxic side effects, and improving bioavailability. Chitosan (CS) has emerged as a promising candidate material for anticancer drug delivery carriers due to its unique physicochemical properties, biocompatibility, and biodegradability. This review summarizes recent research progress on CS nanocarriers for lung cancer treatment and elucidates their challenges and future prospects for clinical transformation.

Indexed as

Antineoplastic AgentsChitosanDrug CarriersDrug Delivery SystemsLung NeoplasmsAnimalsHumansAntineoplastic AgentsChitosanDrug Carrierschitosandrug delivery systemslung cancernanocarriersphototherapy

Identifiers

PMID41169704
PMCPMC12570974

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.