Evidence map›Paper›PMID 41169675›Full record

ReviewScience and technology of advanced materials2025

Emerging novel hydrogels application in oral and gastrointestinal diseases: design wet adhesive strategy towards possible mechanisms.

Rongjun Xiao, Kai Huang, Yuwen Chen, Wentao Jiang, Laijun Xu

Abstract readReview
In one paragraph

Review in Science and technology of advanced materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rongjun XiaoXiangya School of Stomatology, Central South University, Changsha, Hunan, China.
Kai HuangXiangya School of Stomatology, Central South University, Changsha, Hunan, China.
Yuwen ChenSchool of Life Sciences, Central South University, Changsha, Hunan, China.
Wentao JiangSchool of Stomatology, Shandong Second Medical University, Weifang, Shandong, China.
Laijun XuStomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0003-3752-4089

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The humid and highly dynamic milieu of the oral cavity and gastrointestinal tract poses formidable challenges to the precise localization and functionality of drugs and materials. Consequently, materials endowed with intrinsic wet adhesion properties hold great promise for the treatment of oral and gastrointestinal disorders. To a certain extent, the evolution of biomaterials has propelled progress in clinical diagnostics and therapeutic modalities. Wet-adhesive hydrogels, which can adapt to the moist and variable conditions of the digestive tract, display a spectrum of favorable biological attributes, such as antibacterial, anti-inflammatory, antioxidant, and hemostatic effects. These properties render them invaluable in the precision treatment of oral and gastrointestinal diseases. In this review, we scrutinize the adhesion mechanisms of wet-adhesive hydrogels and explore how their biological functions enable them to function efficiently within the gastrointestinal environment.

Indexed as

adhesive propertieshydrogeloral and gastrointestinal diseasesWet adhesion

Identifiers

PMID41169675
PMCPMC12570248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.