ArticlePlastic and reconstructive surgery. Global open2025
Pilot Study Comparing Platelet-rich Plasma Gel Dressings to Conventional Dressings in Treating Acute Facial Burns: A Double-blinded Trial.
Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
5 authors.
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Abstract
Background: Platelet-rich plasma (PRP) contains growth factors essential for tissue repair. This study investigated the effect of PRP gel on superficial facial burns. Methods: In this randomized clinical trial, 30 patients with acute superficial facial burn wounds were divided into 2 groups. The PRP group (n=15) received PRP gel dressings for 2 days. The control group (n=15) used moist exposed burn ointment (beta-sitosterol 0.25% in sesame oil with a beeswax thickener) 3 times daily. Conducted at Kasr Al-Aini Hospital, Cairo, Egypt, from October 2021 to October 2022, the primary outcome was time to complete wound healing, assessed at 1 week, 3 months, and 6 months. Secondary outcomes included postoperative pain (visual analog scale within 48 h), wound infection (within 3 weeks), pigmentation (at 3 and 6 mo), itching score, patient satisfaction (Likert scale at 3 mo), and cosmetic outcomes (modified Vancouver Scar Scale at 3 mo). Results: No significant differences were found in baseline demographics or pain levels (3.67 ± 1.11 versus 4.47 ± 1.96, Conclusions: PRP gel seems to promote faster healing, reduce complications, and enhance patient satisfaction in superficial facial burns, indicating its potential as a therapeutic option.
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