ArticleCase reports in women's health2025
Heterotopic pregnancy following ovulation induction with clomiphene citrate therapy: A case report.
Article in Case reports in women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A heterotopic pregnancy is a rare, life-threatening condition in which an intrauterine and ectopic pregnancy occur simultaneously. The incidence of these pregnancies is increasing as the use of assisted reproductive technology and ovulation-inducing agents becomes more common and accessible. A 31-year-old woman with polycystic ovarian syndrome conceived following clomiphene citrate-induced ovulation and was later diagnosed with a heterotopic pregnancy at 10 weeks 2 days of intrauterine gestation and 9 weeks 2 days of ectopic gestation by transvaginal ultrasound following painless vaginal bleeding and rectal pain. The ectopic pregnancy was managed surgically, and the intrauterine pregnancy progressed to a full-term vaginal delivery. This case calls attention to the importance of physicians maintaining a high index of suspicion for heterotopic pregnancy in patients undergoing ovulation induction, despite reassuring imaging and nonspecific symptoms.
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