Evidence map›Paper›PMID 41169579›Full record

ArticleJACS Au2025

Engineering a Functional Histidine Brace Copper-Binding Site into a

Salvatore La Gatta, Linda Leone, Gianmattia Sgueglia, Lorena Šimunić, Yu-Kai Liao, Ondřej Vaněk, Marco Chino, Flavia Nastri, Mario Chiesa, Angela Lombardi

Abstract read
In one paragraph

Article in JACS Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Salvatore La GattaDepartment of Chemical Sciences, University of Napoli Federico II, Via Cintia 26, 80126 Napoli, Italy.
Linda LeoneDepartment of Chemical Sciences, University of Napoli Federico II, Via Cintia 26, 80126 Napoli, Italy.ORCID https://orcid.org/0000-0001-7293-1814
Gianmattia SguegliaDepartment of Chemical Sciences, University of Napoli Federico II, Via Cintia 26, 80126 Napoli, Italy.ORCID https://orcid.org/0000-0002-8729-179X
Lorena ŠimunićDepartment of Chemical Sciences, University of Napoli Federico II, Via Cintia 26, 80126 Napoli, Italy.
Yu-Kai LiaoDepartment of Chemistry, University of Torino, Via Giuria 9, 10125-Torino, Italy.ORCID https://orcid.org/0000-0002-8090-2025
Ondřej VaněkDepartment of Biochemistry, Faculty of Science, Charles University, Hlavova 2030/8, 12800 Prague, Czech Republic.ORCID https://orcid.org/0000-0003-1190-8535
Marco ChinoDepartment of Chemical Sciences, University of Napoli Federico II, Via Cintia 26, 80126 Napoli, Italy.ORCID https://orcid.org/0000-0002-0436-3293
Flavia NastriDepartment of Chemical Sciences, University of Napoli Federico II, Via Cintia 26, 80126 Napoli, Italy.ORCID https://orcid.org/0000-0002-3390-9822
Mario ChiesaDepartment of Chemistry, University of Torino, Via Giuria 9, 10125-Torino, Italy.ORCID https://orcid.org/0000-0001-8128-8031
Angela LombardiDepartment of Chemical Sciences, University of Napoli Federico II, Via Cintia 26, 80126 Napoli, Italy.ORCID https://orcid.org/0000-0002-2013-3009

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

catalysisde novo protein designhistidine brace copper-binding motiflytic polysaccharide monooxygenase modelspectroscopic characterization

Identifiers

PMID41169579
PMCPMC12569686

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.