Evidence map›Paper›PMID 41169531›Full record

ArticleOpen forum infectious diseases2025

Use of Preventive Measures for Cardiovascular Disease in People With HIV.

Nadine Jaschinski, Bastian Neesgaard, Ferdinand Wit, Marc Van der Valk, Justyna Kowalska, Anna Lisa Ridolfo, Huldrych F Günthard, Marcel Stöckle, Elmar Wallner, Piotr Nowak and 13 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Nadine JaschinskiCHIP, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Bastian NeesgaardCHIP, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Ferdinand WitAIDS Therapy Evaluation in the Netherlands (ATHENA) Cohort, Stichting HIV Monitoring, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0003-2066-8115
Marc Van der ValkAIDS Therapy Evaluation in the Netherlands (ATHENA) Cohort, Stichting HIV Monitoring, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-8290-6425
Justyna KowalskaInfectious Diseases Observational Research Unit, Medical University of Warsaw, Warsaw, Poland.ORCID https://orcid.org/0000-0003-1166-4462
Anna Lisa RidolfoIII Infectious Diseases Unit, ASST Fatebenefratelli-Sacco, Milan, Italy.
Huldrych F GünthardInstitute of Medical Virology, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-1142-6723
Marcel StöckleDivision of Infectious Diseases and Hospital Epidemiology, University Hospital of Basel, University of Basel, Basel, Switzerland.ORCID https://orcid.org/0000-0002-0088-5078
Elmar WallnerLandeskrankenhaus Graz II, Standort West, Department fur Gastroenterologie, Infektiologie, Pneumologie, Graz, Austria.
Piotr NowakSwedish InfCare HIV Cohort, Karolinska University Hospital, Stockholm, Sweden.
Antonella CastagnaSan Raffaele Scientific Institute, Università Vita-Salute San Raffaele, Milano, Italy.ORCID https://orcid.org/0000-0002-8338-9714
Antonella d'Arminio MonforteItalian Cohort Naive Antiretrovirals (ICONA), ASST Santi Paolo e Carlo, Milano, Italy.
Kathy PetoumenosThe Australian HIV Observational Database (AHOD), The Kirby Institute, UNSW, Kensington, NSW, Australia.
Jennifer F HoyDepartment of Infectious Diseases, The Alfred Hospital and Monash University, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0002-6948-7086
Sean HoseinEuropean AIDS Treatment Group (EATG), Brussels, Belgium.
Jens LundgrenCHIP, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Harmony GargesViiV Healthcare, RTP, Durham, North Carolina, USA.
Felipe RogattoGilead Sciences Inc, Foster City, California, USA.
Lital YoungMerck Sharp & Dohme, Rahway, New Jersey, USA.
Lars PetersCHIP, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Amanda MocroftCHIP, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Lene RyomCHIP, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
RESPOND Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Data on uptake of preventive measures for cardiovascular disease (CVD) in people with HIV are limited. Methods: We determined the annual prevalence (2012-2021) of CVD preventive measures use for RESPOND participants with a very high (>10%) estimated D:A:D 10-year CVD risk who were eligible for each specific measure evaluated. We used binomial regression to assess factors associated with each preventative measure uptake. Results: Between 2012 and 2021, the crude proportion of >10% estimated 10-year CVD risk individuals increased from 32.4% (n = 4272) to 52.1% (n = 5298). At the end of follow-up, among very high-risk individuals, 67.4% (1552/2303) with hypertension used antihypertensives, 55.9% (1562/2792) with dyslipidemia lipid-lowering drugs (LLDs), and 7.4% (159/2149) smokers ceased smoking, without significant changes over time. Conversely, a smaller proportion of individuals with diabetes received antidiabetics in later years (2012-2013: 60.3% [388/643] versus 2019-2020: 57.2% [459/803], global Conclusions: The increasing proportion of individuals at very high estimated 10-year CVD risk without a corresponding increase in use of preventive measures calls for greater awareness of CVD risk management for people with HIV attending routine clinical care.

Indexed as

cardiovascular diseasecohortHIV

Identifiers

PMID41169531
PMCPMC12569598

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.