ArticleFrontiers in endocrinology2025
Comparison between 75-g and 100-g oral glucose tolerance tests using international association of diabetes and pregnancy study group one-step diagnostic threshold to detect gestational diabetes mellitus.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Impact of maternal glycemic control during pregnancy on early biomarkers of neonatal metabolic syndrome.Frontiers in pediatrics · 2026Article
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9 authors.
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Abstract
Background: The oral glucose tolerance test (OGTT) is the primary screening method for gestational diabetes mellitus (GDM), but global implementation criteria remain inconsistent. Methods: This retrospective study analyzed data from 3,907 pregnant women at Tongchuan People's Hospital, including 1,925 in the 75g OGTT group (430 with GDM) and 1,982 in the 100g OGTT group (460 with GDM). A systematic comparison was conducted between the two groups regarding: blood glucose levels at each time point (0h, 1h, 2h);diagnostic rates, positive composition ratios of gestational diabetes mellitus, and risks of adverse maternal and neonatal outcomes based on the International Association of Diabetes and Pregnancy Study Groups (IADPSG) diagnostic criteria; Correlation analysis of blood glucose levels across time points; A glucose-level-adjusted continuous analysis to evaluate the dose-response relationship between dynamic glucose changes and adverse maternal and neonatal outcomes in the overall population. Results: The 100g group had significantly higher 1h and 2h blood glucose levels than the 75g group ( Conclusion: Under the IADPSG criteria, no significant differences in diagnostic efficacy were observed between the 75g and 100g OGTT glucose loads for GDM. Standardizing screening strategies to improve clinical consistency is warranted.
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